Name: Anti-Complement Factor B Antibody
Brand: TargetMol
SKU: T9901A-1417
Rating: 4.5 (1 reviews)

生物活性

产品描述	Anti-Complement Factor B Antibody is a highly specialized humanized monoclonal antibody target and neutralize complement factor B, inhibition of the alternative complement pathway by disrupting the enzymatic assembly of the C3 convertase complex across various immunological experimental models.
体外活性	在旁路途径溶血实验中，Anti-Complement Factor B Antibody (13192) 抑制了补体激活，IC50 为 0.5 ug/mL [1]。
体内活性	在小鼠胶原诱导的关节炎模型中，通过全身给药方式给予 2 mg Anti-Complement Factor B Antibody (13192)，显著降低了临床评分并减轻了关节骨破坏 [1]。
别名	抗补体因子 B 抗体
反应种属	Human
应用	ELISA FACS Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1.0 EU/mg

抗体信息

同型

IgG1

偶联与修饰

偶联	Unconjugated

抗原信息

Uniprot ID	P00751
靶点	ComplementFactorB

储存&溶解度

存储

Anti-Complement Factor B Antibody