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Anti-Complement factor H/CFH Antibody (2X509)

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Anti-Complement factor H/CFH Antibody (2X509)
产品编号 TMAC-01422
别名 HUS, HF2, HF1, HF, H factor 1, FHL1, FH, Complement factor H, CFHL3, CFH, ARMS1, ARMD4, AMBP1, AHUS1

Anti-Complement factor H/CFH Antibody (2X509) 是一种 Rabbit 抗体，靶向 Complement factor H/CFH。Anti-Complement factor H/CFH Antibody (2X509) 可用于 WB,ICC。

Anti-Complement factor H/CFH Antibody (2X509)

Anti-Complement factor H/CFH Antibody (2X509)

Rating icon 还可以
Anti-Complement factor H/CFH Antibody (2X509)
产品编号 TMAC-01422 别名 HUS, HF2, HF1, HF, H factor 1, FHL1, FH, Complement factor H, CFHL3, CFH, ARMS1, ARMD4, AMBP1, AHUS1

Anti-Complement factor H/CFH Antibody (2X509) 是一种 Rabbit 抗体，靶向 Complement factor H/CFH。Anti-Complement factor H/CFH Antibody (2X509) 可用于 WB,ICC。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-Complement factor H/CFH Antibody (2X509) is a Rabbit antibody targeting Complement factor H/CFH. Anti-Complement factor H/CFH Antibody (2X509) can be used in WB,ICC.
别名HUS, HF2, HF1, HF, H factor 1, FHL1, FH, Complement factor H, CFHL3, CFH, ARMS1, ARMD4, AMBP1, AHUS1
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of Factor H on human lung tissue lysate using anti-Factor H antibody at 1/1,000 dilution.
2. ICC staining Factor H in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining Factor H in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC
推荐剂量
WB: 1:500-2000; ICC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The Factor H gene family is a multidomain, multifunctional protein family whose individual members are defined by conserved structural elements, which display diverse yet often overlapping functions. These proteins share a common structural motif, the short consensus repeat (SCR), which is structurally conserved among related genes and between phylogenetically divergent species. The human complement Factor H (FH, CFH, HUS, b-1H) gene encodes a 1213 amino acid serum glycoprotein which is arranged into 20 SCRs, each approximately 60 amino acids long, and an 18-residue leader sequence. Factor H controls the function of the alternative complement pathway and acts as a cofactor with Factor I (C3b inactivator). In addition, Factor H has functional activity outside of the complement system, where it can bind to the cellular integrin receptor (CD11b/CD18), interact with cell surface glycosaminoglycans and associate with the surface of certain pathogenic microorganisms. Deficiencies in Factor H is a common characteristic of acute renal disease.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P08603
化学信息
分子量Theoretical: 140 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器

关键词

HF-2HF-1HF 2HF 1FHL-1FHL 1CFHL-3CFHL 3ARMS-1ARMS 1ARMD-4ARMD 4AMBP-1AMBP 1AHUS-1AHUS 1

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