Name: TL1A/TNFSF15 Protein, Mouse, Recombinant (hFc)
Brand: TargetMol
SKU: TMPK-01013
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 358

3日内发货

10 μg

¥ 573

3日内发货

20 μg

¥ 938

3日内发货

50 μg

¥ 1,830

3日内发货

100 μg

¥ 3,100

现货

200 μg

¥ 5,620

5日内发货

500 μg

¥ 12,400

5日内发货

生物活性

产品描述	TNFSF15 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 48.8 kDa and the accession number is Q5UBV8.
生物活性	1. Immobilized Mouse DR3, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Mouse TNFSF15, hFc Tag with the EC50 of 3.1ng/ml determined by ELISA. 2. Mouse TNFSF15, hFc Tag captured on CM5 Chip via Protein A can bind Mouse DR3, His Tag with an affinity constant of 4.56 nM as determined in SPR assay.
研究背景	TL1A and its functional receptor DR3 are members of the TNF/TNFR superfamilies of proteins.TL1A and DR3 are abundantly localized at inflamed intestinal areas of patients with IBD and mice with experimental ileitis or colitis and actively participate in the immunological pathways that underlie mucosal homeostasis and intestinal inflammation.Recently, an important role was demonstrated for TL1A/DR3 as potential mediators of intestinal fibrosis that is associated with the presence of gut inflammation.
种属	Mouse
表达系统	HEK293 Cells
标签	N-hFc
蛋白编号	Q5UBV8
蛋白构建	Ala61-Leu252
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	VEGI-251, VEGI192A, VEGI, TNFSF15, TL1A, TL1
内毒素	< 1 EU/μg by the LAL method.

化学信息

分子量	48.8 kDa (predicted). Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

TL1A/TNFSF15 Protein, Mouse, Recombinant (hFc)

TL1A/TNFSF15 Protein, Mouse, Recombinant (hFc)

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