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Anti-GAD67 Antibody (1N825)
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产品编号 TMAC-01594
别名 SCP, glutamate decarboxylase 1 (brain, 67kDa), GAD, CPSQ1
Anti-GAD67 Antibody (1N825) 是一种 Rabbit 抗体，靶向 GAD67。Anti-GAD67 Antibody (1N825) 可用于 WB,IP。
Anti-GAD67 Antibody (1N825)
Anti-GAD67 Antibody (1N825)
还可以产品编号 TMAC-01594 别名 SCP, glutamate decarboxylase 1 (brain, 67kDa), GAD, CPSQ1
Anti-GAD67 Antibody (1N825) 是一种 Rabbit 抗体，靶向 GAD67。Anti-GAD67 Antibody (1N825) 可用于 WB,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-GAD67 Antibody (1N825) is a Rabbit antibody targeting GAD67. Anti-GAD67 Antibody (1N825) can be used in WB,IP. |
| 别名 | SCP, glutamate decarboxylase 1 (brain, 67kDa), GAD, CPSQ1 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of GAD67 on Hela cells lysates using anti-GAD67 antibody at 1/500 dilution. |
| 应用 | |
| 推荐剂量 | WB: 1:500-1000; IP: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | There are two forms of glutamic acid decarboxylases (GADs) that are found in the brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1, GAD or SCP). GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (g-aminobutyric acid) from L-glutamic acid. Although both GADs are found in the brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 will transiently activate to assist in GABA production. The loss of GAD-65 is detrimental and can impair GABA neurotransmission, however the loss of GAD-67 is lethal. Due to alternative splicing, two isoforms exist for GAD-67, the predominant GAD-67 form and the minor GAD-25 form. GAD-25 is not expressed in brain but can be found in a variety of endocrine tissues. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 67 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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