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Anti-LY75/CD205 Antibody (7F139)
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产品编号 TMAY-00430
别名 Ly-75, LY75, GP200-MR6, DEC-205, CLEC13B, CD205
Anti-LY75/CD205 Antibody (7F139) 是一种 Rabbit 抗体，靶向 LY75/CD205。Anti-LY75/CD205 Antibody (7F139) 可用于 WB。
Anti-LY75/CD205 Antibody (7F139)
331 Anti-LY75/CD205 Antibody (7F139)
还可以产品编号 TMAY-00430 别名 Ly-75, LY75, GP200-MR6, DEC-205, CLEC13B, CD205
Anti-LY75/CD205 Antibody (7F139) 是一种 Rabbit 抗体，靶向 LY75/CD205。Anti-LY75/CD205 Antibody (7F139) 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,289 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-LY75/CD205 Antibody (7F139) is a Rabbit antibody targeting LY75/CD205. Anti-LY75/CD205 Antibody (7F139) can be used in WB. |
| 别名 | Ly-75, LY75, GP200-MR6, DEC-205, CLEC13B, CD205 |
| Ig Type | Rabbit IgG |
| 克隆号 | 7F139 |
| 交叉反应 | Mouse |
| 验证活性 | Anti-S Tag rabbit monoclonal antibody at 1:1000 dilution. -Lane A: S tag-GFERh(C) transfected 293 cell lysate at 1μg -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the N-terminus of the Mouse DEC-205 / LY75. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. It is broadly expressed in the lymph node, appendix, and other tissues. LY75 knockdown in SKOV3 cells resulted in predominant upregulation of functional pathways implicated in cell proliferation and metabolism, while pathways associated with cell signaling and adhesion, complement activation, and immune response were mostly suppressed. Moreover, LY75 suppression had an opposite effect on EOC cell lines with the epithelial phenotype (A2780s and OV2008), by directing epithelial-to-mesenchymal transition (EMT) associated with reduced capacity for in vivo EOC cell colonization, as similar/identical signaling pathways were reversely regulated, when compared to mesenchymal LY75 knockdown EOC cells. Diseases associated with LY75 include Pneumonic Plague and Adenoiditis. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: N-terminus of the Mouse DEC-205 / LY75 |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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