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Anti-RELT/TNFRSF19L Antibody (2H203)
还可以产品编号 TMAY-00952
Anti-RELT/TNFRSF19L Antibody (2H203) 是一种 Mouse 抗体，靶向 RELT/TNFRSF19L。Anti-RELT/TNFRSF19L Antibody (2H203) 可用于 ICC/IF。
Anti-RELT/TNFRSF19L Antibody (2H203)
Anti-RELT/TNFRSF19L Antibody (2H203)
还可以产品编号 TMAY-00952
Anti-RELT/TNFRSF19L Antibody (2H203) 是一种 Mouse 抗体，靶向 RELT/TNFRSF19L。Anti-RELT/TNFRSF19L Antibody (2H203) 可用于 ICC/IF。
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产品介绍
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抗原信息
| 产品描述 | Anti-RELT/TNFRSF19L Antibody (2H203) is a Mouse antibody targeting RELT/TNFRSF19L. Anti-RELT/TNFRSF19L Antibody (2H203) can be used in ICC/IF. |
| Ig Type | Monoclonal Mouse IgG2b |
| 克隆号 | 2H203 |
| 交叉反应 | Human |
| 验证活性 | Confocal immunofluorescence analysis of Human RELT in SKBR3 cells. Cells were fixed with 4% PFA, permeabilzed with 1% Triton X-100 in PBS, blocked with 10% serum, and incubated with Mouse anti-Human RELT monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-mouse IgG secondary antibody (green). Positive staining was localized to cytoplasm and plasma membrane. |
| 应用 | ICC/IF |
| 推荐剂量 | ICC-IF: 1:20-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human RELT / TNFRSF19L (rh RELT / TNFRSF19L; TMPY-01429; NP_116260.2; Met1-Ala160). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Receptor expressed in lymphoid tissues (RELT), also known as tumor necrosis factor receptor superfamily, member 19-like (TNFRSF19L), is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1. RELT/TNFRSF19L is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. RELT/TNFRSF19L is a type I transmembrane glycoprotein with a cysteine-rich extracellular domain, possessing significant homology to other members of the TNFR superfamily, especially TNFRSF19, DR3, OX40, and LTbeta receptor. RELT/TNFRSF19L is able to activate the NF-kappaB pathway and selectively binds tumor necrosis factor receptor-associated factor 1. RELT/TNFRSF19L is able to activate the NF-κB pathway and selectively binds tumor necrosis factor receptor-associated factor 1. Although the soluble form of RELT fusion protein does not inhibit the one-way mixed lymphocyte reaction, immobilized RELT/TNFRSF19L is capable of costimulating T-cell proliferation in the presence of CD3 signaling. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human RELT / TNFRSF19L protein (TMPY-01429) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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