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Anti-HER2/ERBB2 Antibody (8K444)

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Anti-HER2/ERBB2 Antibody (8K444)
产品编号 TMAC-01805
别名 TKR1, NGL, NEU, MLN19, MLN 19, HERVW, HERV7Q, herstatin, HER-2, HER2, ERVWE1, ERBB2, ENVW, ENV, EGFR2, CD340

Anti-HER2/ERBB2 Antibody (8K444) 是一种 Mouse 抗体,靶向 HER2/ERBB2。Anti-HER2/ERBB2 Antibody (8K444) 可用于 IHC,IF,WB。

Anti-HER2/ERBB2 Antibody (8K444)

Anti-HER2/ERBB2 Antibody (8K444)

Rating icon 还可以
Anti-HER2/ERBB2 Antibody (8K444)
产品编号 TMAC-01805 别名 TKR1, NGL, NEU, MLN19, MLN 19, HERVW, HERV7Q, herstatin, HER-2, HER2, ERVWE1, ERBB2, ENVW, ENV, EGFR2, CD340

Anti-HER2/ERBB2 Antibody (8K444) 是一种 Mouse 抗体,靶向 HER2/ERBB2。Anti-HER2/ERBB2 Antibody (8K444) 可用于 IHC,IF,WB。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-HER2/ERBB2 Antibody (8K444) is a Mouse antibody targeting HER2/ERBB2. Anti-HER2/ERBB2 Antibody (8K444) can be used in IHC,IF,WB.
别名TKR1, NGL, NEU, MLN19, MLN 19, HERVW, HERV7Q, herstatin, HER-2, HER2, ERVWE1, ERBB2, ENVW, ENV, EGFR2, CD340
Ig Type
IgG2a, Kappa
克隆号
8K444
交叉反应
Human
验证活性
1. Whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-Her-2(ABT088) antibody. The HRP-conjugated Goat anti-Mouse IgG(H + L) antibody was used to detect the antibody. Lane 1: MCF7, Predicted band size: 137kDa, Observed band size: 200kDa.
2. Whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-Her-2(ABT088) antibody. The HRP-conjugated Goat anti-Mouse IgG(H + L) antibody was used to detect the antibody. Lane 1: SK-BR-3, Predicted band size: 137kDa, Observed band size: 200kDa.
3. Whole cell lysates were separated by 10% SDS-PAGE, and the membrane was blotted with anti-Her-2(ABT008) antibody. The HRP-conjugated Goat anti-Mouse IgG(H + L) antibody was used to detect the antibody. Lane 1: T47D, Predicted band size: 137kDa, Observed band size: 180kDa.
4. Human breast carcinoma tissue was stained with Anti-Her-2 (ABT008) Antibody.
5. Human breast carcinoma tissue was stained with Anti-Her-2 (ABT008) Antibody.
6. Human metastatic hepatocellular carcinoma of the breast tissue was stained with Anti-Her-2 (ABT008) Antibody.
应用
推荐剂量
IHC: 1:100-500 IF: 1:100-500 WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
性状Liquid
缓冲液Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
研究背景This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthesized peptide: human Her-2
抗原种属
human
基因ID
Uniprot ID
化学信息
分子量Theoretical: 137 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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