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MICB Protein, Human, Recombinant (hFc)

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货号 TMPK-00247

别名 PERB11.2, MIC-B, MICB

MICB (MHC class I chain-related gene B) is a transmembrane glycoprotein that functions as a ligand for NKG2D. A closely related protein, MICA, shares 85% amino acid identity with MICB.MICB Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis. MICB Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 58.21 kDa and the accession number is Q29980-1.

MICB Protein, Human, Recombinant (hFc)
其他形式的 “MICB Protein, Human, Recombinant (hFc)”:
MICB Protein, Human, Recombinant (His & Avi)
MICB Protein, Human, Recombinant (His & Avi), Biotinylated
MICB Protein, Human, Recombinant (His & hFc)
MICB Protein, Human, Recombinant (His)

MICB Protein, Human, Recombinant (hFc)

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Rating icon 还可以
SPR兼容缓冲液
货号 TMPK-00247 别名 PERB11.2, MIC-B, MICB

MICB (MHC class I chain-related gene B) is a transmembrane glycoprotein that functions as a ligand for NKG2D. A closely related protein, MICA, shares 85% amino acid identity with MICB.MICB Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis. MICB Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 58.21 kDa and the accession number is Q29980-1.

规格价格库存数量
5 μg
¥ 358
6-8日内发货
10 μg
¥ 573
6-8日内发货
20 μg
¥ 938
5日内发货
50 μg
¥ 1,830
5日内发货
100 μg
¥ 3,100
5日内发货
200 μg
¥ 5,620
5日内发货
500 μg
¥ 12,400
5日内发货
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产品介绍

生物活性
产品描述
MICB (MHC class I chain-related gene B) is a transmembrane glycoprotein that functions as a ligand for NKG2D. A closely related protein, MICA, shares 85% amino acid identity with MICB.MICB Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis. MICB Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 58.21 kDa and the accession number is Q29980-1.
生物活性
1. Immobilized Human MICB, hFc Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-MICB Antibody, hFc Tag with the EC50 of 0.14μml determined by ELISA (QC Test). 2. Human MICB, hFc Tag captured on CM5 Chip via Protein A can bind Human NKG2D, His Tag with an affinity constant of 95.15 nM as determined in SPR assay.
研究背景
MICB (MHC class I chain-related gene B) is a transmembrane glycoprotein that functions as a ligand for NKG2D. A closely related protein, MICA, shares 85% amino acid identity with MICB.MICB Seems to have no role in antigen presentation. Acts as a stress-induced self-antigen that is recognized by gamma delta T cells. Ligand for the KLRK1/NKG2D receptor. Binding to KLRK1 leads to cell lysis.
种属
Human
表达系统
HEK293 Cells
标签C-hFc
蛋白编号Q29980-1
蛋白构建Ala23-Gly298
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状Lyophilized powder
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名PERB11.2, MIC-B, MICB
内毒素< 1 EU/μg by the LAL method.
化学信息
分子量58.21 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice.
存储It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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技术支持

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