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Anti-SPDEF Polyclonal Antibody

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货号 TMAB-13094

Anti-SPDEF Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SPDEF。Anti-SPDEF Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

Anti-SPDEF Polyclonal Antibody

Anti-SPDEF Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-13094

Anti-SPDEF Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SPDEF。Anti-SPDEF Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-SPDEF Polyclonal Antibody is a Rabbit antibody targeting SPDEF. Anti-SPDEF Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Chicken,Dog,Cow,Horse,Rabbit)
应用IHC-PIHC-FrICC/IFIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus (Probable).
组织特异性Expressed in a very restricted set of primarily hormone-regulated epithelial tissues with particularly high expression in the prostate gland. Significantly lower expression is seen in other hormone regulated tissues such as mammary gland, salivary gland, and ovary. Expressed in prostate carcinoma cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景SPDEF, also known as PDEF is an ETS transcription factor expressed in the prostate epithelial cells. It is thought to act as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter and also as a transcriptional activator for the SERPINB5 promoter. It is highly expressed in prostate carcinoma cells and is thought to be involved in the regulation of the prostate gland and/or prostate cancer development. It is also expressed in epithelial breast carcinoma.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PDEF
抗原种属
Human
基因名称
SPDEF
基因ID
蛋白名称
SAM pointed domain-containing Ets transcription factor
Uniprot ID
功能
May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT-3' DNA sequences. May play a role in the regulation of the prostate gland and/or prostate cancer development. Acts as a transcriptional activator for SERPINB5 promoter.
化学信息
分子量Theoretical: 38 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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