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Anti-SPDEF Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SPDEF。Anti-SPDEF Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF。
Anti-SPDEF Polyclonal Antibody 是一种 Rabbit 抗体,靶向 SPDEF。Anti-SPDEF Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-SPDEF Polyclonal Antibody is a Rabbit antibody targeting SPDEF. Anti-SPDEF Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse,Rat (predicted:Chicken,Dog,Cow,Horse,Rabbit) |
| 应用 | IHC-PIHC-FrICC/IFIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus (Probable). |
| 组织特异性 | Expressed in a very restricted set of primarily hormone-regulated epithelial tissues with particularly high expression in the prostate gland. Significantly lower expression is seen in other hormone regulated tissues such as mammary gland, salivary gland, and ovary. Expressed in prostate carcinoma cells. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | SPDEF, also known as PDEF is an ETS transcription factor expressed in the prostate epithelial cells. It is thought to act as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter and also as a transcriptional activator for the SERPINB5 promoter. It is highly expressed in prostate carcinoma cells and is thought to be involved in the regulation of the prostate gland and/or prostate cancer development. It is also expressed in epithelial breast carcinoma. |
| 免疫原 | KLH conjugated synthetic peptide: human PDEF |
| 抗原种属 | Human |
| 基因名称 | SPDEF |
| 基因ID | |
| 蛋白名称 | SAM pointed domain-containing Ets transcription factor |
| Uniprot ID | |
| 功能 | May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT-3' DNA sequences. May play a role in the regulation of the prostate gland and/or prostate cancer development. Acts as a transcriptional activator for SERPINB5 promoter. |
| 分子量 | Theoretical: 38 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |