Overexpression of SERPINB4 in tumor cells inhibited recombinant GrM-induced as well as NK cell-mediated cell death and this inhibition depended on the reactive center loop of the serpin.
生物活性 | Testing in progress |
产品描述 | Overexpression of SERPINB4 in tumor cells inhibited recombinant GrM-induced as well as NK cell-mediated cell death and this inhibition depended on the reactive center loop of the serpin. |
种属 | Human |
表达系统 | Baculovirus Insect Cells |
标签 | N-His |
蛋白编号 | P48594 |
别名 | SCCA-2, LEUPIN, SCCA1, serpin peptidase inhibitor, clade B (ovalbumin), member 4, Serpin B4, SCCA2, PI11 |
蛋白构建 | The Human SERPINB4 (P48594) (Met 1-Pro 390) was expressed, with a polyhistidine tag at the N-terminus. |
蛋白纯度 | > 88 % as determined by SDS-PAGE |
分子量 | 47.1 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 500 mM NaCl, pH 7.4, 20% gly, 1 mM EDTA, 1 mM DTT. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | Overexpression of SERPINB4 in tumor cells inhibited recombinant GrM-induced as well as NK cell-mediated cell death and this inhibition depended on the reactive center loop of the serpin. |
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Serpin B4, Protein, Human, Recombinant (His) SCCA-2 LEUPIN SCCA1 serpin peptidase inhibitor, clade B (ovalbumin), member 4 PI-11 PI 11 Serpin B4 SCCA2 SCCA-1 SCCA 2 PI11 SCCA 1 recombinant recombinant-proteins proteins protein