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Anti-UCHL1 Antibody (8X527)
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产品编号 TMAC-03179
别名 Uch-L1, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), PGP95, PGP9.5, PARK5, NDGOA, HEL-117
Anti-UCHL1 Antibody (8X527) 是一种 Rabbit 抗体，靶向 UCHL1。Anti-UCHL1 Antibody (8X527) 可用于 WB,ICC/IF,IHC,IP。
Anti-UCHL1 Antibody (8X527)
Anti-UCHL1 Antibody (8X527)
还可以产品编号 TMAC-03179 别名 Uch-L1, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), PGP95, PGP9.5, PARK5, NDGOA, HEL-117
Anti-UCHL1 Antibody (8X527) 是一种 Rabbit 抗体，靶向 UCHL1。Anti-UCHL1 Antibody (8X527) 可用于 WB,ICC/IF,IHC,IP。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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| 产品描述 | Anti-UCHL1 Antibody (8X527) is a Rabbit antibody targeting UCHL1. Anti-UCHL1 Antibody (8X527) can be used in WB,ICC/IF,IHC,IP. |
| 别名 | Uch-L1, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), PGP95, PGP9.5, PARK5, NDGOA, HEL-117 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-PGP9.5 antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-PGP9.5 antibody. Counter stained with hematoxylin. 3. ICC staining PGP9.5 in PC-3M cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining PGP9.5 in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining PGP9.5 in PC-12 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| 应用 | |
| 推荐剂量 | WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:100-500; IP: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | UCH-L1 (ubiquitin C-terminal hydrolase) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. UCH-L1 is expressed in brain neurons. Examination of specific brain regions reveals expression in all areas tested, particularly in the substantia nigra. UCH-L1 represents 1-2% of total soluble brain protein. Its occurrence in Lewy bodies and its function in the proteasome pathway make it a compelling candidate gene in Parkinson disease. The gene which encodes UCH-L1 maps to human chromosome 4p13. The 230 amino acid human UCH-L3 protein is 54% identical to that of UCH-L1. UCH-L3 is the predominant thiol protease and has high-affinity binding sites for ubiquitin. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 25 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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