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Anti-LYPLA2 Antibody (2Z810) 是一种 Mouse 抗体,靶向 LYPLA2。Anti-LYPLA2 Antibody (2Z810) 可用于 ELISA。
Anti-LYPLA2 Antibody (2Z810) 是一种 Mouse 抗体,靶向 LYPLA2。Anti-LYPLA2 Antibody (2Z810) 可用于 ELISA。
产品描述 | Anti-LYPLA2 Antibody (2Z810) is a Mouse antibody targeting LYPLA2. Anti-LYPLA2 Antibody (2Z810) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG2b |
克隆号 | 2Z810 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LYPLA2 (rh LYPLA2; TMPY-02132; O95372; Met 1-Val 231). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Lysophospholipase II (LYPLA2, LPL-II, or LysoPLA II), also known as Acyl-protein thioesterase 2 (APT-2), belongs to the AB hydrolase 2 family. This enzyme has lysophospholipase activity and may hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Acyl-protein thioesterase 1 (APT-1) and Acyl-protein thioesterase 2 (APT-2) are cytosolic lysophospholipids hydrolyzing enzymes. The serum activity of APT-1 may play an important role in the determination of the concentration of des-acyl ghrelin in circulation, especially under septic inflammation. APT-2/LYPLA2 is expressed both in CHO-K1 and HeLa cells and its overexpression increased the deacylation rate of single acylated GAP-43 and affected the steady-state localization of diacylated GAP-43 and H-Ras. Thus, the results demonstrate that APT-2/LYPLA2 is the protein thioesterase involved in the acylation/deacylation cycle operating in GAP-43 subcellular distribution. |
偶联 | Unconjugated |
免疫原 | Recombinant Human LYPLA2 protein (TMPY-02132) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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