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Anti-NLRP3 Polyclonal Antibody 4
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产品编号 TMAB-01246
别名 PYRIN-containing APAF1-like protein 1, PYPAF1, NLRP3, NALP3, NACHT, LRR and PYD domains-containing protein 3, LRR and PYD domains-containing protein 3, Cryopyrin, Cold-induced autoinflammatory syndrome 1 protein, CIAS1, Caterpiller protein 1.1 (CLR1.1), C1orf7, Angiotensin/vasopressin receptor AII/AVP-like
Anti-NLRP3 Polyclonal Antibody 4 是一种 Rabbit 抗体，靶向 NLRP3。Anti-NLRP3 Polyclonal Antibody 4 可用于 FCM。
Anti-NLRP3 Polyclonal Antibody 4
Anti-NLRP3 Polyclonal Antibody 4
还可以产品编号 TMAB-01246 别名 PYRIN-containing APAF1-like protein 1, PYPAF1, NLRP3, NALP3, NACHT, LRR and PYD domains-containing protein 3, LRR and PYD domains-containing protein 3, Cryopyrin, Cold-induced autoinflammatory syndrome 1 protein, CIAS1, Caterpiller protein 1.1 (CLR1.1), C1orf7, Angiotensin/vasopressin receptor AII/AVP-like
Anti-NLRP3 Polyclonal Antibody 4 是一种 Rabbit 抗体，靶向 NLRP3。Anti-NLRP3 Polyclonal Antibody 4 可用于 FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-NLRP3 Polyclonal Antibody 4 is a Rabbit antibody targeting NLRP3. Anti-NLRP3 Polyclonal Antibody 4 can be used in FCM. |
| 别名 | PYRIN-containing APAF1-like protein 1, PYPAF1, NLRP3, NALP3, NACHT, LRR and PYD domains-containing protein 3, LRR and PYD domains-containing protein 3, Cryopyrin, Cold-induced autoinflammatory syndrome 1 protein, CIAS1, Caterpiller protein 1.1 (CLR1.1), C1orf7, Angiotensin/vasopressin receptor AII/AVP-like |
| Ig Type | IgG |
| 交叉反应 | Mouse (predicted:Human,Rat) |
| 验证活性 | Blank control (black line): Raw264.7. Primary Antibody (green line): Rabbit Anti-NALP3/CIAS1 antibody (TMAB-01246) Dilution: 1 μg/Test; Secondary Antibody (white blue line): Goat anti-rabbit IgG-AF488 Dilution: 0.5 μg/Test. Isotype control (orange line): Normal Rabbit IgG Protocol The cells were fixed with 4% PFA (10 min at room temperature) and then permeabilized with 90% ice-cold methanol for 20 min at-20°C, The cells were then incubated in 5% BSA to block non-specific protein-protein interactions for 30 min at room temperature. Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. |
| 应用 | |
| 推荐剂量 | FCM: 1ug/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18. Subcellular Location : Cytoplasm. |
| 免疫原 | KLH conjugated synthetic peptide: human Cryopyrin |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | TNF,Inflammatory mediators,Macrophage / Inflamm.,NFkB Pathway |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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