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Anti-CDMP1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CDMP1。Anti-CDMP1 Polyclonal Antibody 可用于 WB。
Anti-CDMP1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CDMP1。Anti-CDMP1 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-CDMP1 Polyclonal Antibody is a Rabbit antibody targeting CDMP1. Anti-CDMP1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse (predicted:Rat,Dog,Pig,Cow,Horse,Rabbit) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Predominantly expressed in long bones during embryonic development. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Defects in GDF5 are the cause of acromesomelic chondrodysplasia Grebe type (AMDG) . Acromesomelic chondrodysplasias are rare hereditary skeletal disorders characterized by short stature, very short limbs, and hand/foot malformations. The severity of limb abnormalities increases from proximal to distal with profoundly affected hands and feet showing brachydactyly and/or rudimentary fingers (knob-like fingers). AMDG is an autosomal recessive form characterized by normal axial skeletons and missing or fused skeletal elements within the hands and feet. Defects in GDF5 are the cause of acromesomelic chondrodysplasia Hunter-Thompson type (AMDH). AMDH is an autosomal recessive form of dwarfism. Patients have limb abnormalities, with the middle and distal segments being most affected and the lower limbs more affected than the upper. AMDH is characterized by normal axial skeletons and missing or fused skeletal elements within the hands and feet. Defects in GDF5 are the cause of brachydactyly type C (BDC). BDC is an autosomal dominant disorder characterized by an abnormal shortness of the fingers and toes. |
| 免疫原 | KLH conjugated synthetic peptide: human CDMP1/GDF5 |
| 抗原种属 | Human |
| 基因名称 | GDF5 |
| 基因ID | |
| 蛋白名称 | Growth/differentiation factor 5 |
| Uniprot ID | |
| 功能 | Could be involved in bone and cartilage formation. Chondrogenic signaling is mediated by the high-affinity receptor BMPR1B. |
| 分子量 | Theoretical: 55 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |