购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍化学信息储存和溶解信息计算器技术支持

RAB2 Protein, Mouse, Recombinant (His)

一键复制产品信息
Rating icon 还可以
SPR兼容缓冲液
货号 TMPY-00610

别名 RAB2A, member RAS oncogene family, Rab2, C80220, 9330148M11Rik

RAB2A, a protein essential for ER-to-Golgi transport, is critical in promoting proteolytic activity and 3D invasiveness of breast cancer (BC) cell lines.RAB2A is amplified and elevated in human BC and is a powerful and independent predictor of disease recurrence in BC patients. Thus, RAB2A is a novel trafficking determinant essential for regulation of a mesenchymal invasive program of BC dissemination. At the cellular levels, RAB2A controls both canonical polarized Golgi-to-Plasma membrane trafficking of the junctional protein E-cadherin, and post-endocytic trafficking of the membrane-bound metalloprotease, MT1-MMP.

RAB2 Protein, Mouse, Recombinant (His)
TargetMol

为众多的药物研发团队赋能，

让新药发现更简单！

RAB2 Protein, Mouse, Recombinant (His)

一键复制产品信息
Rating icon 还可以
SPR兼容缓冲液
货号 TMPY-00610 别名 RAB2A, member RAS oncogene family, Rab2, C80220, 9330148M11Rik

RAB2A, a protein essential for ER-to-Golgi transport, is critical in promoting proteolytic activity and 3D invasiveness of breast cancer (BC) cell lines.RAB2A is amplified and elevated in human BC and is a powerful and independent predictor of disease recurrence in BC patients. Thus, RAB2A is a novel trafficking determinant essential for regulation of a mesenchymal invasive program of BC dissemination. At the cellular levels, RAB2A controls both canonical polarized Golgi-to-Plasma membrane trafficking of the junctional protein E-cadherin, and post-endocytic trafficking of the membrane-bound metalloprotease, MT1-MMP.

规格价格库存数量
5 μg
¥ 493
6-8日内发货
10 μg
¥ 790
6-8日内发货
20 μg
¥ 1,330
5日内发货
50 μg
¥ 2,580
5日内发货
100 μg
¥ 5,170
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:
重组蛋白用户指南

产品介绍

生物活性
产品描述
RAB2A, a protein essential for ER-to-Golgi transport, is critical in promoting proteolytic activity and 3D invasiveness of breast cancer (BC) cell lines.RAB2A is amplified and elevated in human BC and is a powerful and independent predictor of disease recurrence in BC patients. Thus, RAB2A is a novel trafficking determinant essential for regulation of a mesenchymal invasive program of BC dissemination. At the cellular levels, RAB2A controls both canonical polarized Golgi-to-Plasma membrane trafficking of the junctional protein E-cadherin, and post-endocytic trafficking of the membrane-bound metalloprotease, MT1-MMP.
生物活性
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
RAB2A, a protein essential for ER-to-Golgi transport, is critical in promoting proteolytic activity and 3D invasiveness of breast cancer (BC) cell lines.RAB2A is amplified and elevated in human BC and is a powerful and independent predictor of disease recurrence in BC patients. Thus, RAB2A is a novel trafficking determinant essential for regulation of a mesenchymal invasive program of BC dissemination. At the cellular levels, RAB2A controls both canonical polarized Golgi-to-Plasma membrane trafficking of the junctional protein E-cadherin, and post-endocytic trafficking of the membrane-bound metalloprotease, MT1-MMP.
种属
Mouse
表达系统
E. coli
标签N-His
蛋白编号P53994
蛋白构建A DNA sequence encoding the mouse Rab2a (NP_067493.1) (Met1-Cys212) was expressed with a polyhistidine tag at the N-terminus. Predicted N terminal: Met
蛋白纯度
> 95 % as determined by SDS-PAGE
蛋白性状Lyophilized powder
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名RAB2A, member RAS oncogene family, Rab2, C80220, 9330148M11Rik
内毒素Please contact us for more information.
化学信息
分子量25.8 kDa (predicted)
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice.
存储It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
  • 比活力 计算器

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.

关键词

C-80220C 80220
Related Tags: buy RAB2 Protein, Mouse, Recombinant (His) | purchase RAB2 Protein, Mouse, Recombinant (His) | RAB2 Protein, Mouse, Recombinant (His) cost | order RAB2 Protein, Mouse, Recombinant (His) | RAB2 Protein, Mouse, Recombinant (His) chemical structure | RAB2 Protein, Mouse, Recombinant (His) molecular weight