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Anti-SLAM/CD150 Polyclonal Antibody
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产品编号 TMAB-01698
别名 SLAM, signaling lymphocytic activation molecule family member 1, CDw150, CD150
Anti-SLAM/CD150 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SLAM/CD150。Anti-SLAM/CD150 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,ELISA。
Anti-SLAM/CD150 Polyclonal Antibody
Anti-SLAM/CD150 Polyclonal Antibody
还可以产品编号 TMAB-01698 别名 SLAM, signaling lymphocytic activation molecule family member 1, CDw150, CD150
Anti-SLAM/CD150 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SLAM/CD150。Anti-SLAM/CD150 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
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产品介绍
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抗原信息
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| 产品描述 | Anti-SLAM/CD150 Polyclonal Antibody is a Rabbit antibody targeting SLAM/CD150. Anti-SLAM/CD150 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,ELISA. |
| 疾病造模方案 | |
| 别名 | SLAM, signaling lymphocytic activation molecule family member 1, CDw150, CD150 |
| Ig Type | IgG |
| 交叉反应 | Mouse,Rat (predicted:Human,Dog,Pig,Cow,Horse,Sheep) |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein. Note=Present on the surface of B-cells and T-cells. |
| 组织特异性 | Constitutively expressed on peripheral blood memory T-cells, T-cell clones, immature thymocytes and a proportion of B-cells, and is rapidly induced on naive T-cells after activation. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | SLAM, a novel glycoprotein of 37kDa, designated SLAM (Signaling Lymphocyte Activation Molecule) or CDw150, belongs to the immunoglobulin gene superfamily and is involved in T cell stimulation. SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. Activated B cells express the membrane bound form of SLAM and the soluble and cytoplasmic isoforms of SLAM, and the expression levels of membrane bound SLAM on B cells are rapidly regulated after activation in vitro. It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells. |
| 免疫原 | KLH conjugated synthetic peptide: human CD150 |
| 抗原种属 | Human |
| 基因名称 | SLAMF1 |
| 基因ID | |
| 蛋白名称 | Signaling lymphocytic activation molecule |
| Uniprot ID | |
| 研究领域 | Endothelial Cell Markers,Non-lineage,Host Virus Interaction,HSC markers,Surface Molecules |
| 功能 | High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates. |
| 分子量 | Theoretical: 70 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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