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Anti-MAP2 Antibody (1T377) 是一种 Mouse 抗体,靶向 MAP2。Anti-MAP2 Antibody (1T377) 可用于 IHC-P,IHC-Fr,IF。
Anti-MAP2 Antibody (1T377) 是一种 Mouse 抗体,靶向 MAP2。Anti-MAP2 Antibody (1T377) 可用于 IHC-P,IHC-Fr,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,170 | 5日内发货 | |
100 μL | ¥ 1,970 | 5日内发货 | |
200 μL | ¥ 2,785 | 5日内发货 |
产品描述 | Anti-MAP2 Antibody (1T377) is a Mouse antibody targeting MAP2. Anti-MAP2 Antibody (1T377) can be used in IHC-P,IHC-Fr,IF. |
Ig Type | IgG1 |
克隆号 | 1T377 |
交叉反应 | Human |
验证活性 | Paraformaldehyde-fixed, paraffin embedded (Human brain glioma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (MAP2) Monoclonal Antibody, Unconjugated (TMAB-01099) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Mouse) instructionsand DAB staining. |
应用 | |
推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
亚细胞定位 | Cytoplasm, cytoskeleton (Probable). |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | Protein G purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | MAP2 is the major microtubule associated protein of brain tissue. There are three forms of MAP2; two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c). In the newborn rat brain, MAP2b and MAP2c are present, while MAP2a is absent. Between postnatal days 10 and 20, MAP2a appears. At the same time, the level of MAP2c drops by 10-fold. This change happens during the period when dendrite growth is completed and when neurons have reached their mature morphology. MAP2 is degraded by a Cathepsin D-like protease in the brain of aged rats. There is some indication that MAP2 is expressed at higher levels in some types of neurons than in other types. MAP2 is known to promote microtubule assembly and to form side-arms on microtubules. It also interacts with neurofilaments, actin, and other elements of the cytoskeleton. |
免疫原 | Recombinant Protein: human MAP2 protein |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | Dendrite marker,Soma marker,map2,MAP,Neuron Restricted Lineage |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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