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Anti-MAP2 Antibody (1T377)

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Anti-MAP2 Antibody (1T377)
产品编号 TMAB-01099

Anti-MAP2 Antibody (1T377) 是一种 Mouse 抗体,靶向 MAP2。Anti-MAP2 Antibody (1T377) 可用于 IHC-P,IHC-Fr,IF。

Anti-MAP2 Antibody (1T377)

Anti-MAP2 Antibody (1T377)

Rating icon 还可以
Anti-MAP2 Antibody (1T377)
产品编号 TMAB-01099

Anti-MAP2 Antibody (1T377) 是一种 Mouse 抗体,靶向 MAP2。Anti-MAP2 Antibody (1T377) 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-MAP2 Antibody (1T377) is a Mouse antibody targeting MAP2. Anti-MAP2 Antibody (1T377) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG1
克隆号
1T377
交叉反应
Human
验证活性
Paraformaldehyde-fixed, paraffin embedded (Human brain glioma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (MAP2) Monoclonal Antibody, Unconjugated (TMAB-01099) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Mouse) instructionsand DAB staining.
应用
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cytoplasm, cytoskeleton (Probable).
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景MAP2 is the major microtubule associated protein of brain tissue. There are three forms of MAP2; two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c). In the newborn rat brain, MAP2b and MAP2c are present, while MAP2a is absent. Between postnatal days 10 and 20, MAP2a appears. At the same time, the level of MAP2c drops by 10-fold. This change happens during the period when dendrite growth is completed and when neurons have reached their mature morphology. MAP2 is degraded by a Cathepsin D-like protease in the brain of aged rats. There is some indication that MAP2 is expressed at higher levels in some types of neurons than in other types. MAP2 is known to promote microtubule assembly and to form side-arms on microtubules. It also interacts with neurofilaments, actin, and other elements of the cytoskeleton.
抗原信息
免疫原
Recombinant Protein: human MAP2 protein
抗原种属
Human
基因ID
Uniprot ID
研究领域
Dendrite marker,Soma marker,map2,MAP,Neuron Restricted Lineage
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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