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Anti-Phospho-EphA2/5 (Tyr594) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-EphA2/5 (Tyr594)。Anti-Phospho-EphA2/5 (Tyr594) Polyclonal Antibody 可用于 WB。
Anti-Phospho-EphA2/5 (Tyr594) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-EphA2/5 (Tyr594)。Anti-Phospho-EphA2/5 (Tyr594) Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,245 | 5日内发货 |
产品描述 | Anti-Phospho-EphA2/5 (Tyr594) Polyclonal Antibody is a Rabbit antibody targeting Phospho-EphA2/5 (Tyr594). Anti-Phospho-EphA2/5 (Tyr594) Polyclonal Antibody can be used in WB. |
别名 | p-EphA2/5 (Y594), p-EphA2/5 (Tyr594), EphA2/5 (p-Y594), EphA2/5 (p-Tyr594) |
Ig Type | IgG |
交叉反应 | Human,Mouse |
验证活性 | 1. Western blot analysis of extracts from JK cells (Lane 2), using EPHA2/5 (Phospho-Tyr594) Antibody TMAC-01316. The lane on the left is treated with antigen-specific peptide. |
应用 | |
推荐剂量 | WB: 1:500-1000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of tyrosine 594 (H-T-Y(p)-E-D) derived from Human EPHA2/5 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 110 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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