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顶部生物活性储存和溶解信息计算器

Anti-SEMA4D Monoclonal Antibody

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产品编号 TMAZ-0130
别名 Semaphorin-4D, GR3, BB18, A8

Anti-SEMA4D Monoclonal Antibody is a humanized rabbit antibody targeting SEMA4D. Anti-SEMA4D Monoclonal Antibody can be used in ELISA, FCM. 可用于 ELISA,FCM。

Anti-SEMA4D Monoclonal Antibody

Anti-SEMA4D Monoclonal Antibody

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产品编号 TMAZ-0130 别名 Semaphorin-4D, GR3, BB18, A8

Anti-SEMA4D Monoclonal Antibody is a humanized rabbit antibody targeting SEMA4D. Anti-SEMA4D Monoclonal Antibody can be used in ELISA, FCM. 可用于 ELISA,FCM。

规格价格库存数量
10 μg
¥ 746
In stock
25 μg
¥ 1,239
7日内发货
50 μg
¥ 1,486
7日内发货
100 μg
¥ 2,080
7日内发货
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浓度:0.38 mg/mL
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产品介绍

生物活性
产品描述
Anti-SEMA4D Monoclonal Antibody is a humanized rabbit antibody targeting SEMA4D. Anti-SEMA4D Monoclonal Antibody can be used in ELISA,FCM.
别名Semaphorin-4D, GR3, BB18, A8
Ig Type
Rabbit monoclonal IgG
交叉反应
Human
验证活性
Flow cytometry analysis of SEMA4D overexpressed 293F cells with TMAZ-0130BI, followed by goat anti-rabbit IgG-ABflo 647 (red). The isotype control is rabbit IgG (black line).
应用ELISAFCM
推荐剂量
0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Single-pass type I membrane
构建方式This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of SEMA4D protein.
纯化方式Protein A Affinity Purified
性状Liquid
缓冲液0.22 μm filtered solution in PBS.
纯度> 95% as determined by SDS-PAGE.
研究背景Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling (PubMed: 20877282). Regulates GABAergic synapse development (By similarity). Promotes the development of inhibitory synapses in a PLXNB1-dependent manner (By similarity). Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA (PubMed: 19788569). Promotes the migration of cerebellar granule cells (PubMed: 16055703). Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro) (PubMed: 8876214). Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway (PubMed: 16055703)
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Biotin
可提供抗体种类
2
抗原信息
免疫原
SEMA4D
抗原种属
Human
基因ID
10507
Uniprot ID
Q92854
研究领域
Cancer Research
化学信息
分子量150 kDa
颜色Transparent
物理性状Liquid
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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