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Flusilazole

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纯度: 99.64%

货号 T20835Cas号 85509-19-9

别名 氟硅唑, Sanction, Olymp, Nustar, Flusilazol, DPX-6573, DPX6573

Flusilazole (DPX6573) 是一种具有广谱抗真菌作用的有机硅杀菌剂。 Flusilazole 可用于控制多种蔬菜和水果的真菌感染。

Flusilazole
其他形式的 “Flusilazole”:

Flusilazole

一键复制产品信息
Rating icon 很棒

纯度: 99.64%

货号 T20835 别名 氟硅唑, Sanction, Olymp, Nustar, Flusilazol, DPX-6573, DPX6573Cas号 85509-19-9

Flusilazole (DPX6573) 是一种具有广谱抗真菌作用的有机硅杀菌剂。 Flusilazole 可用于控制多种蔬菜和水果的真菌感染。

规格价格库存数量
25 mg
¥ 99
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50 mg
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产品介绍


Flusilazole AI Summary
Flusilazole is a bioactive molecule with significant impacts on various signaling pathways and notable antifungal properties. It functions as an agonist of retinoid X receptor alpha, peroxisome proliferator-activated receptor delta, rat pregnane X receptor, and human pregnane X receptor signaling pathways, and as an antagonist of farnesoid X receptor and retinoid X receptor alpha signaling, with potencies ranging from 7943.3 nM to 31622.8 nM. In agricultural applications, Flusilazole demonstrates considerable in vivo antifungal activity. Pre-treatment with 2 µg/ml led to a 78.0% reduction in wheat leaf rust caused by Puccinia recondita, with complete control at 10 µg/ml. It also significantly reduces the disease index of cucumber infected with Cladosporium cucumerinum by 95.56% when applied as a 40% SC formulation. Additionally, Flusilazole shows potent fungicidal activity against several fungal species, including Diplodia mutila, Neofusicoccum luteum, Leptosphaeria biglobosa, Leptosphaeria maculans, Oculimacula yallundae, and Oculimacula acuformis, effectively inhibiting mycelial growth, conidial germination, and ascospore germination at low concentrations. For example, it achieves significant inhibition of mycelial growth in Leptosphaeria biglobosa and Leptosphaeria maculans with ED50 values of 0.67 µg/ml and 0.27 µg/ml, respectively. It also inhibits pathogen activity in Neofusicoccum luteum infected Pinot noir grapevines, and demonstrates fungitoxicity against Monilinia laxa strains with EC50 values ranging from 0.1 to 0.4 µg/ml. When applied to plant foliage at 20 ppm, Flusilazole achieves high disease control efficacies of 99.0% against Phaeosphaeria nodorum and 98.0% against Oculimacula yallundae. Its efficacy also extends to prochloraz-resistant isolates of Oculimacula spp., showcasing its potential as a broad-spectrum antifungal agent..
Note: Summary generated by AI. Data source: ChEMBL
生物活性
产品描述
Flusilazole (DPX6573) is an organosilicon fungicide with broad spectrum antifungal effects. Flusilazole can be used to control fungal infections on a variety of vegetables and fruits.
别名氟硅唑, Sanction, Olymp, Nustar, Flusilazol, DPX-6573, DPX6573
化学信息
分子量315.39
分子式C16H15F2N3Si
CAS No.85509-19-9
SmilesC[Si](Cn1cncn1)(c1ccc(F)cc1)c1ccc(F)cc1
密度1.17 g/cm3
储存&溶解度
存储Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
溶解度信息
DMSO: 95 mg/mL (301.21 mM), Sonication is recommended.
体内实验配方
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (10.46 mM), Sonication is recommended.
请按顺序添加溶剂,在添加下一种溶剂之前,尽可能使溶液澄清。如有必要,可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考,体内配方并不是绝对的,请根据不同情况进行调整。
溶液配制表
DMSO
1mg5mg10mg50mg
1 mM3.1707 mL15.8534 mL31.7068 mL158.5339 mL
5 mM0.6341 mL3.1707 mL6.3414 mL31.7068 mL
10 mM0.3171 mL1.5853 mL3.1707 mL15.8534 mL
20 mM0.1585 mL0.7927 mL1.5853 mL7.9267 mL
50 mM0.0634 mL0.3171 mL0.6341 mL3.1707 mL
100 mM0.0317 mL0.1585 mL0.3171 mL1.5853 mL

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法:
比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL, 一共给药动物10只,您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH2O, 那么您的工作液浓度为2 mg/mL
母液配置方法:2 mg 药物溶于 100 μL DMSO ( 母液浓度为 20 mg/mL ), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:100 μL DMSO 母液, 添加 400 μL PEG300 混匀澄清, 再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH2O 混匀澄清
以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。
方案所需的各类助溶剂如: DMSOPEG300PEG400Tween 80SBE-β-CD玉米油等, 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成,不同的产品配方组成不同,如有配方需求,可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算,您也可以参考 更多

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