A2073 is a flavonoid derivative that inhibits the proliferation of erythroleukemia cells by inducing cell cycle arrest and suppressing the MAPK, NF-κB, and PI3K signaling pathways. It forms stable interactions with cell cycle-related proteins (CDK1, CCNA2, PRIM1). In a zebrafish xenograft tumor model, A2073 demonstrates significant anti-tumor cell proliferation activity while maintaining low toxicity. A2073 is suitable for research in acute erythroleukemia.