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Anti-ADK Antibody (5U907)

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Anti-ADK Antibody (5U907)
产品编号 TMAY-02506
别名 AK, adenosine kinase

Anti-ADK Antibody (5U907) 是一种 Rabbit 抗体,靶向 ADK。Anti-ADK Antibody (5U907) 可用于 ELISA。

Anti-ADK Antibody (5U907)

Anti-ADK Antibody (5U907)

Rating icon 还可以
Anti-ADK Antibody (5U907)
产品编号 TMAY-02506 别名 AK, adenosine kinase

Anti-ADK Antibody (5U907) 是一种 Rabbit 抗体,靶向 ADK。Anti-ADK Antibody (5U907) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,294
5日内发货
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产品介绍

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产品描述
Anti-ADK Antibody (5U907) is a Rabbit antibody targeting ADK. Anti-ADK Antibody (5U907) can be used in ELISA.
别名AK, adenosine kinase
Ig Type
Rabbit IgG
克隆号
5U907
交叉反应
Human
应用
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human ADK (rh ADK; TMPY-04473; AAH03568.1; Met1-His345).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Adenosine kinase(ADK) belongs to the family of transferases. Adenosine kinase (ADK) is the key enzyme in adenosine metabolism and catalyzes ATP and adenosine into two products: ADP and AMP. Two isoforms of the enzyme adenosine kinase (ADK), which differ at their N-terminal ends, are found in mammalian cells. It has been shown that the two ADK isoforms differ only in their first exons and the promoter regions; hence they arise via differential splicing of their first exons with the other exons common to both isoforms. In adult brain, ADK is primarily present in astrocytes. Several lines of experimental evidence support a critical role of ADK in different types of brain injury associated with astrogliosis, which is also a prominent morphologic feature of temporal lobe epilepsy (TLE). It has been suggested that dysregulation of ADK in astrocytes is a common pathologic hallmark of TLE. Moreover, in vitro data suggest the existence of an additional layer of modulatory crosstalk between the astrocyte-based adenosine cycle and inflammation. ADK also contributes to CK homeostasis in vivo.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human ADK protein (TMPY-04473)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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