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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Gemin 6 Polyclonal Antibody

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货号 TMAB-06432

Anti-Gemin 6 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Gemin 6。Anti-Gemin 6 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Gemin 6 Polyclonal Antibody

Anti-Gemin 6 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-06432

Anti-Gemin 6 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Gemin 6。Anti-Gemin 6 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Gemin 6 Polyclonal Antibody is a Rabbit antibody targeting Gemin 6. Anti-Gemin 6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus; nucleoplasm. Nucleus; gem. Cytoplasm. Found both in the nucleoplasm and in nuclear bodies called gems (Gemini of Cajal bodies) that are often in proximity to Cajal (coiled) bodies. Also found in the cytoplasm.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord. SMA is caused by deletion or loss-of-function mutations in the SMN (Survival of Motor Neuron) gene. Gemin6, the protein product of human chromosome 2p22.2, associates directly with SMN and is a part of the SMN complex containing Gemin2, Gemin3, Gemin4 and Gemin5 as well as several spliceosomal snRNP proteins. The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus. The SMN complex is found in both the cytoplasm and the nucleus. The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies).
抗原信息
免疫原
KLH conjugated synthetic peptide: human Gemin 6
抗原种属
Human
基因名称
GEMIN6
基因ID
79833
蛋白名称
Gem-associated protein 6
Uniprot ID
Q8WXD5
功能
The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus.
化学信息
分子量Theoretical: 19 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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