Name: PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated
Brand: TargetMol
SKU: TMPK-00471
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 568

6-8日内发货

10 μg

¥ 928

6-8日内发货

20 μg

¥ 1,530

5日内发货

50 μg

¥ 2,970

5日内发货

100 μg

¥ 5,180

5日内发货

200 μg

¥ 9,390

5日内发货

500 μg

¥ 20,700

5日内发货

生物活性

产品描述	Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth. PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 42.7 kDa and the accession number is A0A1B0GS01.
生物活性	1. Immobilized Mouse Nectin-2, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Mouse PVRIG, hFc Tag with the EC50 of 1.76μg/ml determined by ELISA. 2. Biotinylated Mouse PVRIG, hFc-Avi Tag captured on CM5 Chip via Protein A can bind Mouse Nectin-2, His Tag with an affinity constant of 2.22 μM as determined in SPR assay.
研究背景	Murine PVRIG interacted weakly with poliovirus receptor (PVR) but bound poliovirus receptor-like 2 (PVRL2) strongly, making the latter its principal ligand.PVRIG is an inducible checkpoint receptor and that targeting PVRIG-PVRL2 interactions results in increased CD8+ T-cell function and reduced tumor growth.
种属	Mouse
表达系统	HEK293 Cells
标签	C-hFc-Avi
蛋白编号	A0A1B0GS01
蛋白构建	Ser35-Asp165
蛋白纯度	> 95% as determined by Tris-Bis PAGE
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	RMO1, RalGDS/AF-6, PVRIG, PREL-2, PREL2, MGC2463, MGC138297, MGC104322, LPD, CD112R, C7orf15, ALS2CR9, ALS2CR18
内毒素	< 1 EU/μg by the LAL method.

化学信息

分子量	42.7 kDa (predicted). Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated

PVRIG Protein, Mouse, Recombinant (hFc & Avi), Biotinylated

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