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顶部生物活性储存和溶解信息计算器

Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963)

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Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963)
产品编号 TMAC-03264
别名 p-INPP5D (Y1020), p-INPP5D (Tyr1020), INPP5D (p-Y1020), INPP5D (p-Tyr1020)

Anti-Phospho-INPP5D (Y1020) Antibody (3P963) 是一种 Rabbit 抗体，靶向 Phospho-INPP5D (Y1020)。Anti-Phospho-INPP5D (Y1020) Antibody (3P963) 可用于 WB,ICC,IP。

Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963)

Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963)

Rating icon 还可以
Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963)
产品编号 TMAC-03264 别名 p-INPP5D (Y1020), p-INPP5D (Tyr1020), INPP5D (p-Y1020), INPP5D (p-Tyr1020)

Anti-Phospho-INPP5D (Y1020) Antibody (3P963) 是一种 Rabbit 抗体，靶向 Phospho-INPP5D (Y1020)。Anti-Phospho-INPP5D (Y1020) Antibody (3P963) 可用于 WB,ICC,IP。

规格价格库存数量
50 μL
¥ 1,480
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100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963) 是一种 Rabbit 抗体，靶向 Phospho-INPP5D (Tyr1020)。Anti-Phospho-INPP5D (Tyr1020) Antibody (3P963) 可用于 WB,ICC,IP。
别名p-INPP5D (Y1020), p-INPP5D (Tyr1020), INPP5D (p-Y1020), INPP5D (p-Tyr1020)
Ig Type
IgG
交叉反应
Human
验证活性
1. ICC staining Phospho-SHIP (Y1020) in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
2. ICC staining Phospho-SHIP (Y1020) in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining Phospho-SHIP (Y1020) in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC
IP
推荐剂量
WB: 1:1000; ICC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The major translational product of the v-Fms oncogene, originally isolated from the McDonough strain of feline sarcoma virus, has been identified as a glycoprotein with intrinsic tyrosine kinase activity. The v-Fms human cellular homolog, c-Fms, has been molecularly cloned and mapped to band q34 on chromosome 5, and identified as the receptor for hematopoietic ligand, CSF-1. Ligand-induced activation of the intrinsic CSF-1R protein tyrosine kinase triggers its interaction with cytoplasmic effector molecules. One such effector molecule, SHIP-1 p145 (SH2-containing-inositol phosphatase), associates with activated Fms. SHIP-1 contains two phosphotyrosine-binding domains (PTB), a unique amino terminal SH2 domain, a proline-rich region, and two highly conserved motifs found among inositol phosphate 5-phosphatases. SHIP-1 displays both phosphatidylinositol 3,4,5-triphosphate and inositol 1,3,4,5-tetrakisphosphate polyphosphate 5-phosphatase activity. Evidence suggests that SHIP-1 may modulate Ras signaling in addition to inositol signaling pathways.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
A synthesized phosphopeptide: human SHIP around the phosphorylation site of Tyr1020
抗原种属
human
Uniprot ID
Q92835
化学信息
分子量Theoretical: 133 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

pINPP5D (Y1020)pINPP5D (Tyr1020)INPP5D (pY1020)INPP5D (pTyr1020)INPP5D (phospho-Y1020)INPP5D (phospho-Tyr1020)

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