TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (LlaFc)

Synonyms: TIMD-3, TIMD3, TIMD 3, TIM-3, Tim-3, TIM3, TIM 3, T-cell membrane protein 3, T-cell immunoglobulin mucin receptor 3, T-cell immunoglobulin and mucin domain-containing protein 3, KIM-3, KIM3, KIM 3, hepatitis A virus cellular receptor 2, Hepatitis A virus cellular receptor 2, HAVcr-2, HAVCR-2, HAVCR2, HAVCR 2, FLJ-14428, FLJ14428, FLJ 14428, CD-366, CD366, CD 366, FLJ14428

规格

价格

库存

数量

5 μg

¥ 523

5日内发货

10 μg

¥ 791

5日内发货

20 μg

¥ 1,260

5日内发货

50 μg

¥ 2,280

5日内发货

100 μg

¥ 3,660

5日内发货

200 μg

¥ 5,820

5日内发货

500 μg

¥ 10,800

5日内发货

生物活性

产品描述	TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (LlaFc) is expressed in HEK293 Cells. The accession number is Q8TDQ0-1.
生物活性	Immobilized Human TIM-3, LIama Fc Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-TIM-3 Antibody, hFc Tag with the EC50 of 0.14 μg/ml determined by ELISA (QC Test).
研究背景	Hepatitis A virus cellular receptor 2 (HAVCR2), also known as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), is a protein that in humans is encoded by the HAVCR2 gene.TIM3 is an immune checkpoint and together with other inhibitory receptors including programmed cell death protein 1 (PD-1) and lymphocyte activation gene 3 protein (LAG3) mediate the CD8 T-cell exhaustion. TIM3 has also been shown as a CD4 Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.
种属	Human
表达系统	HEK293 Cells
标签	C-Llama Fc
蛋白编号	Q8TDQ0-1
蛋白构建	Ser22-Arg200
蛋白纯度	> 95% as determined by Bis-Tris PAGE
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	TIMD-3, TIMD3, TIMD 3, TIM-3, Tim-3, TIM3, TIM 3, T-cell membrane protein 3, T-cell immunoglobulin mucin receptor 3, T-cell immunoglobulin and mucin domain-containing protein 3, KIM-3, KIM3, KIM 3, hepatitis A virus cellular receptor 2, Hepatitis A virus cellular receptor 2, HAVcr-2, HAVCR-2, HAVCR2, HAVCR 2, FLJ-14428, FLJ14428, FLJ 14428, CD-366, CD366, CD 366, FLJ14428
内毒素	< 0.1 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	47.18 kDa (Predicted); 70-90 kDa (Reducing condition, due to glycosylation)

储存&溶解度

运输方式

In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.

存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (LlaFc)

TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (LlaFc)

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