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Anti-Midkine Antibody (9X800)
还可以产品编号 TMAY-00520
别名 NEGF2, MK, midkine (neurite growth-promoting factor 2), ARAP
Anti-Midkine Antibody (9X800) 是一种 Mouse 抗体，靶向 Midkine。Anti-Midkine Antibody (9X800) 可用于 ELISA。
Anti-Midkine Antibody (9X800)
Anti-Midkine Antibody (9X800)
还可以产品编号 TMAY-00520 别名 NEGF2, MK, midkine (neurite growth-promoting factor 2), ARAP
Anti-Midkine Antibody (9X800) 是一种 Mouse 抗体，靶向 Midkine。Anti-Midkine Antibody (9X800) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,689 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Midkine Antibody (9X800) is a Mouse antibody targeting Midkine. Anti-Midkine Antibody (9X800) can be used in ELISA. |
| 别名 | NEGF2, MK, midkine (neurite growth-promoting factor 2), ARAP |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 9X800 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Midkine (rh Midkine; TMPY-02172; P21741; Met1-Asp143). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Midkine (MK or MDK) also known as neurite growth-promoting factor 2 (NEGF2) is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin. Midkine is a retinoic acid-responsive, heparin-binding growth factor expressed in various cell types during embryogenesis. It promotes angiogenesis, cell growth, and cell migration. Midkine is also expressed in several carcinomas, suggesting that it may play a role in tumorigenesis, perhaps through its effects on angiogenesis. Midkine binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase and the induction of cell proliferation. Midkine is involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development. Midkine exhibited increased expression in the breast carcinomas but showed much lower expression in the normal breast tissue. Thus, it can be used as a breast carcinomas marker. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Midkine Protein (TMPY-02172) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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