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Anti-ARNTL2 Polyclonal Antibody
还可以产品编号 TMAB-00147
别名 wu:fj90c09, Transcription factor BMAL2, Transcription factor BMAL 2, PASD9, PASD 9, MOP9, MOP 9, MGC158186, MGC149672, MGC149671, MGC124257, Member of PAS protein 9, CYCLE-like factor, CLIF, Brain and muscle ARNT like 2, BMAL2, BMAL 2, BMA L2, bHLHe6, Basic-helix-loop-helix-PAS protein MOP9, Aryl hydrocarbon receptor nuclear translocator like 2, ARNTL2, ARNTL 2, ARNT L2
Anti-ARNTL2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ARNTL2。Anti-ARNTL2 Polyclonal Antibody 可用于 WB。
Anti-ARNTL2 Polyclonal Antibody
Anti-ARNTL2 Polyclonal Antibody
一键复制产品信息 还可以产品编号 TMAB-00147 别名 wu:fj90c09, Transcription factor BMAL2, Transcription factor BMAL 2, PASD9, PASD 9, MOP9, MOP 9, MGC158186, MGC149672, MGC149671, MGC124257, Member of PAS protein 9, CYCLE-like factor, CLIF, Brain and muscle ARNT like 2, BMAL2, BMAL 2, BMA L2, bHLHe6, Basic-helix-loop-helix-PAS protein MOP9, Aryl hydrocarbon receptor nuclear translocator like 2, ARNTL2, ARNTL 2, ARNT L2
Anti-ARNTL2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 ARNTL2。Anti-ARNTL2 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
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| 产品描述 | Anti-ARNTL2 Polyclonal Antibody is a Rabbit antibody targeting ARNTL2. Anti-ARNTL2 Polyclonal Antibody can be used in WB. |
| 别名 | wu:fj90c09, Transcription factor BMAL2, Transcription factor BMAL 2, PASD9, PASD 9, MOP9, MOP 9, MGC158186, MGC149672, MGC149671, MGC124257, Member of PAS protein 9, CYCLE-like factor, CLIF, Brain and muscle ARNT like 2, BMAL2, BMAL 2, BMA L2, bHLHe6, Basic-helix-loop-helix-PAS protein MOP9, Aryl hydrocarbon receptor nuclear translocator like 2, ARNTL2, ARNTL 2, ARNT L2 |
| Ig Type | IgG |
| 交叉反应 | Mouse,Rat (predicted:Human) |
| 验证活性 | Sample: Lane 1: Testis (Mouse) Lysate at 40 μg Lane 2: Testis (Rat) Lysate at 40 μg Primary: Anti-ARNTL2 (TMAB-00147) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 71/63 kDa Observed band size: 65 kDa  |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nuclear |
| 组织特异性 | Expressed in fetal brain. Highly expressed in brain and placenta. Lower levels in heart, liver, thymus, kidney and lung. Located to endothelial cells and neuronal cells of the suprachiasmatic nucleus (SCN). Also detected in endothelial cells of the heart, |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | BMAL2 is a 636 amino acid protein that localizes to the nucleus and contains one bHLH (basic helix-loop-helix) domain, one PAC (PAS-associated C-terminal) domain and two PAS (PER-ARNT-SIM) domains. Expressed at high levels in placenta and brain and at lower levels in liver, thymus, heart, lung and kidney, BMAL2 functions as a component of the circadian core oscillator, which includes a variety of proteins that work in tandem to activate the transcription of target genes. More specifically, BMAL2, when functioning as a component of the core oscillator, binds to the E-box element (3'-CACGTG-5') of target DNA, thus inducing transcription. Multiple isoforms of BMAL2 exist due to alternative splicing events. |
| 免疫原 | KLH conjugated synthetic peptide: human ARNTL2 |
| 抗原种属 | Human |
| 基因名称 | ARNTL2 |
| 基因ID | |
| 蛋白名称 | Aryl hydrocarbon receptor nuclear translocator-like protein 2 |
| Uniprot ID | |
| 研究领域 | Cardiac metabolism,Transcription factors/regulators,HLH,Transcription Factors,Receptors |
| 功能 | ARNTL2 (aryl hydrocarbon receptor nuclear translocator-like 2) is a basic Helix-Loop-Helix-Per-Arnt-Sim (bHLH-PAS) transcription factor. ARNTL2-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription. Also, in umbilical vein endothelial cells, ARNTL2 activates SERPINE1 through E-box sites. This transactivation is inhibited by PER2 and CRY1. It may participate in circadian clock regulation |
| 分子量 | Theoretical: 71 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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