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MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST)

MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST)

产品编号 TMPY-04365
别名: SAPKK3, mitogen-activated protein kinase kinase 6, MKK6, MAPKK6, MEK6, PRKMK6, SAPKK-3

MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 65.3 kDa and the accession number is P52564-1.

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MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST)
规格 价格/CNY 货期 数量
50 μg ¥ 3,170 5日内发货
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产品目录号及名称: MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST) (TMPY-04365)
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参考文献
生物活性 The specific activity was determined to be >200 nmol/min/mg using inactive MAPK14 as substrate.
产品描述 MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 65.3 kDa and the accession number is P52564-1.
种属 Human
表达系统 Baculovirus Insect Cells
标签 His, GST
蛋白编号 P52564-1
别名 SAPKK3, mitogen-activated protein kinase kinase 6, MKK6, MAPKK6, MEK6, PRKMK6, SAPKK-3
蛋白构建 The Human MAP2K6 isoform 1 (P52564-1) (Met 1-Asp 334, Ser 207/Asp, Thr 211/Asp) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
蛋白纯度 > 88 % as determined by SDS-PAGE
分子量 65.3 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Supplied as sterile 20 mM Tris, 500 mM NaCl, pH 8.0, 10% glycerol.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store the product under sterile conditions at -20℃ to -80℃. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice.

研究背景 Dual specificity mitogen-activated protein kinase kinase 6, also known as MAP kinase kinase 6, MAPKK 6, MAPK / ERK kinase 6, SAPKK3, MAP2K6, and MKK6, is a protein that belongs to the protein kinase superfamily, STE Ser / Thr protein kinase family and MAP kinase kinase subfamily. MAP2K6 / MKK6 contains one protein kinase domain. Mitogen-activated protein kinases are members of a conserved cascade of kinases involved in many signal transduction pathways. They stimulate phosphorylation of transcription factors in response to extracellular signals such as growth factors, cytokines, ultraviolet light, and stress-inducing agents. MAP2K6 / MKK6 exists in a variety of alternatively spliced isoforms with distinct patterns of tissue expression. Isoform 2 of MAP2K6 / MKK6 is only expressed in skeletal muscle. Isoform 1 of MAP2K6 / MKK6 is expressed in skeletal muscle, heart, and to a lesser extent in liver or pancreas.

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Keywords

MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST) SAPKK3 MEK 6 mitogen-activated protein kinase kinase 6 MKK6 PRKMK-6 PRKMK 6 MAPKK6 MKK 6 MAPKK 6 MAPKK-6 MEK6 MKK-6 PRKMK6 SAPKK-3 SAPKK 3 MEK-6 recombinant recombinant-proteins proteins protein

 

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