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Anti-S100A3 Antibody (7W848) 是一种 Rabbit 抗体,靶向 S100A3。Anti-S100A3 Antibody (7W848) 可用于 ELISA。
Anti-S100A3 Antibody (7W848) 是一种 Rabbit 抗体,靶向 S100A3。Anti-S100A3 Antibody (7W848) 可用于 ELISA。
产品描述 | Anti-S100A3 Antibody (7W848) is a Rabbit antibody targeting S100A3. Anti-S100A3 Antibody (7W848) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 7W848 |
交叉反应 | Mouse |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse S100A3 (rM S100A3; TMPY-03335; NP_035440.1; Met1-Gln101). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Protein S100-A3, also known as Protein S-100E, S100 calcium-binding protein A3, S100A3 and S100E, is a member of the S-100 family. S100A3 / S100E contains 2 EF-hand domains. S100A3 / S100E is highly expressed in the differentiating cuticular cells within the hair follicle and organized into mature hair cuticles. High concentrations of S100A3 homotetramer might provide the millimolar level of Ca2+required for hair cuticular barrier formation. S100A3 / S100E is a unique member of the Ca2+-binding S100 protein family with the highest cysteine content and affinity for Zn2+. S100A3 / S100E binds both calcium and zinc. S100A3 / S100E probably binds 2 zinc ions per molecule. It may be involved in calcium-dependent cuticle cell differentiation and hair shaft formation. S100A3 plays an important role in calcium-dependent processes leading to hair shaft formation. S100A3 / S100E is a unique protein among all members of the calcium-binding S100 family, is specifically expressed at the inner endocuticle of human hair fibers. Upon hair damage, S100A3 / S100E is released from hair fibers and possibly destabilizes the hair tissue architecture. |
偶联 | Unconjugated |
免疫原 | Recombinant Mouse S100A3 Protein (TMPY-03335) |
抗原种属 | Mouse |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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