Name: Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Brand: TargetMol
SKU: TMPY-03878
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 562

3日内发货

10 μg

¥ 918

3日内发货

20 μg

¥ 1,520

3日内发货

50 μg

¥ 2,970

3日内发货

100 μg

¥ 5,120

现货

200 μg

¥ 9,030

5日内发货

500 μg

¥ 19,000

5日内发货

生物活性

产品描述	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
生物活性	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of ITGAV&ITGB6 via clathrin-mediated endocytosis promotes carcinoma cell invasion.
种属	Human
表达系统	HEK293 Cells
标签	C-Flag, C-His
蛋白编号	P06756-1&P18564-1
蛋白构建	A DNA sequence encoding the extracellular domain (Met 1-Val992) of human ITGAV (P06756-1) was fused with a flag tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the extracellular domain (Met1-Asn707) of human ITGB6 (P18564-1) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 2. The two plasmids were co-expressed and the human ITGAV&ITGB6 heterodimer was purified. Predicted N terminal: Phe 31 & Gly 22
蛋白纯度	> 95 % as determined by SDS-PAGE
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
别名	ITGAV & ITGB6, integrin, α5 (fibronectin receptor, α polypeptide), integrin, alpha 5 (fibronectin receptor, alpha polypeptide), Integrin α V β 6, Integrin alpha V β6
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.