Claudin-18.2 Protein, Human, Recombinant (His)

Claudin-18.2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-8xHis tag. The predicted molecular weight is 18 KDa and the accession number is P56856-2.

规格	价格/CNY		数量
10 μg	￥ 1,970	5日内发货
50 μg	￥ 4,260	5日内发货
500 μg	￥ 17,400	5日内发货
1 mg	￥ 27,800	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 1,970

5日内发货

50 μg

￥ 4,260

5日内发货

500 μg

￥ 17,400

5日内发货

1 mg

￥ 27,800

5日内发货

产品描述	Claudin-18.2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-8xHis tag. The predicted molecular weight is 18 KDa and the accession number is P56856-2.

种属	Human
表达系统	E. coli
标签	N-8xHis
蛋白编号	P56856-2
别名	Claudin-18, CLDN18
氨基酸序列	Asp28-Leu76
蛋白构建	Asp28-Leu76
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	18 KDa (reducing condition)

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Supplied as a 0.2 μm filtered solution of 25 mM Tris-HCl, 25 mM NaCl, 0.1% Triton X-100, 10% glycerol, 0.1 mM GSH, 0.01 mM GSSG, pH 8.0.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Claudin-18(CLDN18) is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. CLDN18 plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. CLDN18 has two isoform A1 and isoform A2. IMAB362 (Claudiximab) is a monoclonal antibody against isoform 2 of Claudin-18. It is under investigation for the treatment of gastrointestinal adenocarcinomas and pancreatic tumors. IMAB362 was developed by Ganymed Pharmaceuticals AG.

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Claudin-18.2 Protein, Human, Recombinant (His)

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