购物车
- 全部删除
您的购物车当前为空
Anti-BCL2 Antibody-FITC (5A692)
还可以产品编号 TMAY-00066F
Anti-BCL2 Antibody-FITC (5A692) 是一种 FITC-conjugated Rabbit 抗体，靶向 BCL2。Anti-BCL2 Antibody-FITC (5A692) 可用于 FCM。
Anti-BCL2 Antibody-FITC (5A692)
Anti-BCL2 Antibody-FITC (5A692)
还可以产品编号 TMAY-00066F
Anti-BCL2 Antibody-FITC (5A692) 是一种 FITC-conjugated Rabbit 抗体，靶向 BCL2。Anti-BCL2 Antibody-FITC (5A692) 可用于 FCM。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-BCL2 Antibody-FITC (5A692) is a FITC-conjugated Rabbit antibody targeting BCL2. Anti-BCL2 Antibody-FITC (5A692) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 5A692 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human BCL2 expression on Jurkat cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with FITC-conjugated anti-Human BCL2. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the N-terminus of the Human Bcl-2, and it was conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family and all members contain at least one of four BH (bcl-2 homology) domains. Certain members such as Bcl-2, Bcl-xl and Mcl1 are anti-apoptotic, whilst others are pro-apoptotic. Most Bcl-2 family members contain a C-terminal transmembrane domain that functions to target these proteins to the outer mitochondrial and other intracellular membranes. It is expressed in a variety of tissues. BCL2 blocks the apoptotic death of some cells such as lymphocytes. It also regulates cell death by controlling the mitochondrial membrane permeability and inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | FITC |
| 其他可选修饰符 | Unconjugated/APC/PerCP/PE |
| 可提供抗体种类 | 5 |
| 免疫原 | A synthetic peptide corresponding to the N-terminus of the Human Bcl-2. |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-BCL2 Antibody-FITC (5A692) | purchase Anti-BCL2 Antibody-FITC (5A692) | Anti-BCL2 Antibody-FITC (5A692) cost | order Anti-BCL2 Antibody-FITC (5A692)
嗨！有任何问题？点我咨询
评论内容