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Anti-CYFIP1 Antibody (1Z411)

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货号 TMAB-04859

Anti-CYFIP1 Antibody (1Z411) 是一种 Rabbit 抗体,靶向 CYFIP1。Anti-CYFIP1 Antibody (1Z411) 可用于 WB,ICC/IF,FCM。

Anti-CYFIP1 Antibody (1Z411)

Anti-CYFIP1 Antibody (1Z411)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04859

Anti-CYFIP1 Antibody (1Z411) 是一种 Rabbit 抗体,靶向 CYFIP1。Anti-CYFIP1 Antibody (1Z411) 可用于 WB,ICC/IF,FCM。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍


生物活性
产品描述
Anti-CYFIP1 Antibody (1Z411) is a Rabbit antibody targeting CYFIP1. Anti-CYFIP1 Antibody (1Z411) can be used in WB,ICC/IF,FCM.
Ig Type
IgG
克隆号
1Z411
反应种属
Human,Mouse,Rat
应用WBICC/IFFCM
推荐剂量
WB: 1:1000-2000; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm > perinuclear region. Cell projection > lamellipodium. Cell projection > ruffle. Cell junction > synapse > synaptosome. Highly expressed in the perinuclear region. Enriched in synaptosomes, membrane ruffles and at the tips of lamellipodia.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity).
抗原信息
免疫原
A synthesized peptide: human CYFIP1
抗原种属
Human
基因名称
CYFIP1
基因ID
蛋白名称
Cytoplasmic FMR1-interacting protein 1
Uniprot ID
功能
Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth. Binds to F-actin but not to RNA. Regulator of epithelial morphogenesis. May act as an invasion suppressor in cancers.
化学信息
分子量Theoretical: 145 kDa. Actual: 130 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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