Name: LRIG1 Protein, Mouse, Recombinant (His)
Brand: TargetMol
SKU: TMPY-02264
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 330

6-8日内发货

10 μg

¥ 533

6-8日内发货

20 μg

¥ 857

5日内发货

50 μg

¥ 1,750

5日内发货

100 μg

¥ 2,960

5日内发货

200 μg

¥ 5,360

5日内发货

500 μg

¥ 13,200

5日内发货

生物活性

产品描述	Leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) is a tumor suppressor and a negative regulator of several receptor tyrosine kinases. Leucine-rich repeats and immunoglobulin-like domains containing protein 1 (LRIG1) is an endogenous feedback regulator of receptor tyrosine kinases (RTKs) and was recently shown to inhibit the growth of different types of malignancies. Leucine-rich repeats and immunoglobulin-like domains 1(LRIG1)is a kind of transmembrane glycoprotein, which is induced by epidermal growth factor (EGF) and develops inhibitory negative feedback by specific binding with epidermal growth factor receptor (EGFR). LRIG1 expression is broadly decreased in human cancer and breast cancer and low expression of LRIG1 has been linked to decreased relapse-free survival.
生物活性	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	Leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) is a tumor suppressor and a negative regulator of several receptor tyrosine kinases. Leucine-rich repeats and immunoglobulin-like domains containing protein 1 (LRIG1) is an endogenous feedback regulator of receptor tyrosine kinases (RTKs) and was recently shown to inhibit the growth of different types of malignancies. Leucine-rich repeats and immunoglobulin-like domains 1(LRIG1)is a kind of transmembrane glycoprotein, which is induced by epidermal growth factor (EGF) and develops inhibitory negative feedback by specific binding with epidermal growth factor receptor (EGFR). LRIG1 expression is broadly decreased in human cancer and breast cancer and low expression of LRIG1 has been linked to decreased relapse-free survival.
种属	Mouse
表达系统	HEK293 Cells
标签	C-His
蛋白编号	P70193
蛋白构建	A DNA sequence encoding the extracellular domain of mouse LRIG1 (NP_032403.2) (Met 1-Thr 794) was expressed, with a polyhistidine tag at the C-terminus. Predicted N terminal: Ala 35
蛋白纯度	> 95 % as determined by SDS-PAGE
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名	LIG-1, leucine-rich repeats and immunoglobulin-like domains 1, Img, D6Bwg0781e
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	85 kDa (predicted); 90-100 kDa (reducing condition, due to glycosylation)

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

LRIG1 Protein, Mouse, Recombinant (His)

LRIG1 Protein, Mouse, Recombinant (His)

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