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Anti-Integrin beta 3 Antibody (4P677)

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产品编号 TMAC-02181
别名 PTP, Platelet membrane glycoprotein IIIa, platelet glycoprotein IIIa precursor, Platelet glycoprotein IIIa, Platelet fibrinogen receptor beta subunit, NAIT, ITGB 3, ITG B3, ITB3, Integrin beta-3, Integrin beta chain, β3 precursor, Integrin beta chain beta 3, Integrin beta 3(platelet glycoprotein IIIa antigen CD61), HPA 4, HPA 1, GPIIIa, GP3A, CD61 antigen, CD61, CD 61

Anti-Integrin beta 3 Antibody (4P677) 是一种 Rabbit 抗体，靶向 Integrin beta 3。Anti-Integrin beta 3 Antibody (4P677) 可用于 ICC/IF,IHC,WB。

Anti-Integrin beta 3 Antibody (4P677)

Anti-Integrin beta 3 Antibody (4P677)

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Rating icon 还可以
产品编号 TMAC-02181 别名 PTP, Platelet membrane glycoprotein IIIa, platelet glycoprotein IIIa precursor, Platelet glycoprotein IIIa, Platelet fibrinogen receptor beta subunit, NAIT, ITGB 3, ITG B3, ITB3, Integrin beta-3, Integrin beta chain, β3 precursor, Integrin beta chain beta 3, Integrin beta 3(platelet glycoprotein IIIa antigen CD61), HPA 4, HPA 1, GPIIIa, GP3A, CD61 antigen, CD61, CD 61

Anti-Integrin beta 3 Antibody (4P677) 是一种 Rabbit 抗体，靶向 Integrin beta 3。Anti-Integrin beta 3 Antibody (4P677) 可用于 ICC/IF,IHC,WB。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-Integrin beta 3 Antibody (4P677) is a Rabbit antibody targeting Integrin beta 3. Anti-Integrin beta 3 Antibody (4P677) can be used in ICC/IF,IHC,WB.
别名PTP, Platelet membrane glycoprotein IIIa, platelet glycoprotein IIIa precursor, Platelet glycoprotein IIIa, Platelet fibrinogen receptor beta subunit, NAIT, ITGB 3, ITG B3, ITB3, Integrin beta-3, Integrin beta chain, β3 precursor, Integrin beta chain beta 3, Integrin beta 3(platelet glycoprotein IIIa antigen CD61), HPA 4, HPA 1, GPIIIa, GP3A, CD61 antigen, CD61, CD 61
Ig Type
IgG
克隆号
4P677
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of Integrin beta 3 on HUVEC cells lysates using anti-Integrin beta 3 antibody at 1/1,000 dilution.
2. Western blotting analysis using Integrin beta 3 Antibody TMAC-02181.
3. TMAC-02181 at 1/100 staining human spleen cancer by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody.
4. TMAC-02181 at 1/100 staining human liver cancer by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody.
5. TMAC-02181 at 1/100 staining human breast cancer by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody.
6. TMAC-02181 at 1/100 staining mouse testis by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody.
7. TMAC-02181 at 1/100 staining mouse colon by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the secondary antibody.
8. ICC staining Integrin beta 3 in HepG2 Cells(red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
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应用ICC/IFIHCWB
推荐剂量
WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P05106
化学信息
分子量Theoretical: 87 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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