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Anti-Estrogen Related Receptor beta Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Estrogen Related Receptor beta。Anti-Estrogen Related Receptor beta Polyclonal Antibody 可用于 WB。
Anti-Estrogen Related Receptor beta Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Estrogen Related Receptor beta。Anti-Estrogen Related Receptor beta Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
| 产品描述 | Anti-Estrogen Related Receptor beta Polyclonal Antibody is a Rabbit antibody targeting Estrogen Related Receptor beta. Anti-Estrogen Related Receptor beta Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Rabbit) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nuclear |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| 浓度 | 1mg/ml |
| 研究背景 | Estrogen related receptor beta, a NR3 Steroid Receptor, has been shown to affect early placental development. Also it can act as a repressor of transcriptional activity mediated by the glucocorticoid receptor (GR). It binds as a monomer to the extended half-site TNAAGTGCA and as a homodimer to the estrogen response element (ERE), palindromic thyroid hormone response element (TRE(pal)), and SF-1 response element, but not to the glucocorticoid response element (GRE). Estrogen related receptor beta mutations lead to abnormal development of the chorion and defective diploid trophoblast proliferation, and are lethal during midgestation. Expression has been documented in mice in the extraembryonic ectoderm that gives rise to the chorion. ESTs have been isolated from normal human eye, lung, and testis libraries. The ligand for the receptor is PPARgamma coactivator 1 (PGC-1) beta. |
| 免疫原 | KLH conjugated synthetic peptide: human Estrogen Related Receptor beta |
| 抗原种属 | Human |
| 基因名称 | ESRRB |
| 基因ID | |
| 蛋白名称 | Steroid hormone receptor ERR2 |
| Uniprot ID | |
| 功能 | Nuclear receptor that binds DNA as monomer. |
| 分子量 | Theoretical: 56 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |