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Anti-CLEC2 Polyclonal Antibody

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货号 TMAB-04448

Anti-CLEC2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CLEC2。Anti-CLEC2 Polyclonal Antibody 可用于 FCM。

Anti-CLEC2 Polyclonal Antibody

Anti-CLEC2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-04448

Anti-CLEC2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CLEC2。Anti-CLEC2 Polyclonal Antibody 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-CLEC2 Polyclonal Antibody is a Rabbit antibody targeting CLEC2. Anti-CLEC2 Polyclonal Antibody can be used in FCM.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Cow)
应用FCM
推荐剂量
FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Single-pass type II membrane protein (Probable).
组织特异性Expressed preferentially in the liver. Also expressed in immune cells of myeloid origin and on the surface of platelets.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011]
抗原信息
免疫原
KLH conjugated synthetic peptide: human CLEC2
抗原种属
Human
基因名称
CLEC1B
基因ID
蛋白名称
C-type lectin domain family 1 member B
Uniprot ID
功能
Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. Acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets.
化学信息
分子量Theoretical: 27 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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