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Anti-CLEC2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CLEC2。Anti-CLEC2 Polyclonal Antibody 可用于 FCM。
Anti-CLEC2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CLEC2。Anti-CLEC2 Polyclonal Antibody 可用于 FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-CLEC2 Polyclonal Antibody is a Rabbit antibody targeting CLEC2. Anti-CLEC2 Polyclonal Antibody can be used in FCM. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat,Cow) |
| 应用 | FCM |
| 推荐剂量 | FCM: 1μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane; Single-pass type II membrane protein (Probable). |
| 组织特异性 | Expressed preferentially in the liver. Also expressed in immune cells of myeloid origin and on the surface of platelets. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011] |
| 免疫原 | KLH conjugated synthetic peptide: human CLEC2 |
| 抗原种属 | Human |
| 基因名称 | CLEC1B |
| 基因ID | |
| 蛋白名称 | C-type lectin domain family 1 member B |
| Uniprot ID | |
| 功能 | Acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. Acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets. |
| 分子量 | Theoretical: 27 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |