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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-ENPP2 Antibody (5B899)

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货号 TMAY-01839

别名 PDNP2, PD-Iα, PD-IALPHA, NPP2, LysoPLD, ectonucleotide pyrophosphatase/phosphodiesterase 2, AUTOTAXIN, ATX-X, ATX

Anti-ENPP2 Antibody (5B899) 是一种 Mouse 抗体，靶向 ENPP2。Anti-ENPP2 Antibody (5B899) 可用于 ELISA。

Anti-ENPP2 Antibody (5B899)

Anti-ENPP2 Antibody (5B899)

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货号 TMAY-01839 别名 PDNP2, PD-Iα, PD-IALPHA, NPP2, LysoPLD, ectonucleotide pyrophosphatase/phosphodiesterase 2, AUTOTAXIN, ATX-X, ATX

Anti-ENPP2 Antibody (5B899) 是一种 Mouse 抗体，靶向 ENPP2。Anti-ENPP2 Antibody (5B899) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 1,679
5日内发货
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产品介绍

生物活性
产品描述
Anti-ENPP2 Antibody (5B899) is a Mouse antibody targeting ENPP2. Anti-ENPP2 Antibody (5B899) can be used in ELISA.
别名PDNP2, PD-Iα, PD-IALPHA, NPP2, LysoPLD, ectonucleotide pyrophosphatase/phosphodiesterase 2, AUTOTAXIN, ATX-X, ATX
Ig Type
Mouse IgG2b
克隆号
5B899
反应种属
Human
特异性
Human Autotaxin/ENPP-2
应用ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Autotaxin/ENPP2 (rh Autotaxin/ENPP2; TMPY-02778; AAH34961.1; Asp49-Ile863). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The Autotaxin protein is important for generating the lipid signaling molecule lysophosphatidic acid (LPA), which is a potent mitogen, which facilitates cell proliferation and migration, neurite retraction, platelet aggregation, smooth muscle contraction, actin stress formation and cytokine and chemokine secretion. ATX has been found to catalyze the formation of cyclic phosphatidic acid (cPA), which have antitumor role by antimitogenic regulation of cell cycle, inhibition of cancer invasion and metastasis. LPA receptors and ATX are upregulated in numerous cancer cell types and show expression patterns that correlate with tumor cell invasiveness. Thus, Autotaxin has recently emerged as an attractive target for the development of anti-cancer chemotherapeutics. In addition, Serum ATX activity was found to be enhanced in relation to hepatic fibrosis in chronic liver disease due to hepatitis virus C infection.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human Autotaxin/ENPP2 Protein (TMPY-02778)
抗原种属
Human
研究领域
Phosphatases and Regulators
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.
存储-20°C for 1 year

计算器

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关键词

PDNP-2PDNP 2NPP-2NPP 2
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