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Anti-ERR1 Antibody (5B243) 是一种 Rabbit 抗体,靶向 ERR1。Anti-ERR1 Antibody (5B243) 可用于 WB,IP,FCM。
Anti-ERR1 Antibody (5B243) 是一种 Rabbit 抗体,靶向 ERR1。Anti-ERR1 Antibody (5B243) 可用于 WB,IP,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-ERR1 Antibody (5B243) is a Rabbit antibody targeting ERR1. Anti-ERR1 Antibody (5B243) can be used in WB,IP,FCM. |
别名 | Steroid hormone receptor ERR1, Nuclear receptor subfamily 3 group B member 1, NR3B1, Estrogen-related receptor alpha (ERR-alpha), Estrogen receptor-like 1, ESRRA, ESRL1, ERR1 |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of Estrogen Related Receptor alpha on MCF-7 cell lysates using anti-Estrogen Related Receptor alpha antibody at 1/1,000 dilution. 2. Flow cytometric analysis of Hela cells with Estrogen Related Receptor alpha antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
应用 | |
推荐剂量 | WB: 1:1000-2000; FCM: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Estrogen related receptor alpha (ERRα) is a nuclear receptor in the superfamily of ligand-regulated transcription factors and is a member of the NR3B orphan nuclear receptor subgroup (consisting of α, β and γ). ERRα plays a role in modulating the estrogen signaling pathway. In addition, the expression of ERRα has been shown to increase during fasting and cold exposure. ERRα may be important for regulating mitochondrial biogenesis and oxidative metabolism by acting directly on genes necessary for mitochondrial function. Mice lacking ERRα are unable to maintain their body temperature in the cold. ERRα may also be involved in the maintenance and formation of cartilage. This information could be useful in finding therapeutic agents for a variety of diseases affecting the joints. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 53 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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