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顶部生物活性储存和溶解信息计算器

Anti-HDAC2 Antibody (5Z519)

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Anti-HDAC2 Antibody (5Z519)
产品编号 TMAC-01774
别名 Histone deacetylase 2, HDAC 2, HD2, EC 3.5.1.98

Anti-HDAC2 Antibody (5Z519) 是一种 Rabbit 抗体，靶向 HDAC2。Anti-HDAC2 Antibody (5Z519) 可用于 WB,IP。

Anti-HDAC2 Antibody (5Z519)

Anti-HDAC2 Antibody (5Z519)

Rating icon 还可以
Anti-HDAC2 Antibody (5Z519)
产品编号 TMAC-01774 别名 Histone deacetylase 2, HDAC 2, HD2, EC 3.5.1.98

Anti-HDAC2 Antibody (5Z519) 是一种 Rabbit 抗体，靶向 HDAC2。Anti-HDAC2 Antibody (5Z519) 可用于 WB,IP。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-HDAC2 Antibody (5Z519) is a Rabbit antibody targeting HDAC2. Anti-HDAC2 Antibody (5Z519) can be used in WB,IP.
别名Histone deacetylase 2, HDAC 2, HD2, EC 3.5.1.98
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of HDAC2 on different lysates using anti-HDAC2 antibody at 1/1,000 dilution. Positive control: Lane 1: K562, Lane 2: Hela.
应用
WB
IP
推荐剂量
WB: 1:1000-2000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (for p300/CBP-associated factor), p300/CBP and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1) and HDAC2 (also designated mammalian RPD3), both of which are related to the yeast transcriptional regulator Rpd3p, have been identified as histone deacetylases.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q92769
化学信息
分子量Theoretical: 60 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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