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Anti-HSD17B1 Antibody (6P431)

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货号 TMAB-07316

Anti-HSD17B1 Antibody (6P431) 是一种 Rabbit 抗体,靶向 HSD17B1。Anti-HSD17B1 Antibody (6P431) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-HSD17B1 Antibody (6P431)

Anti-HSD17B1 Antibody (6P431)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07316

Anti-HSD17B1 Antibody (6P431) 是一种 Rabbit 抗体,靶向 HSD17B1。Anti-HSD17B1 Antibody (6P431) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍


生物活性
产品描述
Anti-HSD17B1 Antibody (6P431) is a Rabbit antibody targeting HSD17B1. Anti-HSD17B1 Antibody (6P431) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
6P431
反应种属
Human
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:1000-5000; IHC-P: 1:1000-5000; IHC-Fr: 1:1000-5000; IF: 1:1000-5000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the 17beta-hydroxysteroid dehydrogenase family of short-chain dehydrogenases/reductases. It has a dual function in estrogen activation and androgen inactivation and plays a major role in establishing the estrogen E2 concentration gradient between serum and peripheral tissues. The encoded protein catalyzes the last step in estrogen activation, using NADPH to convert estrogens E1 and E2 and androgens like 4-androstenedione, to testosterone. It has an N-terminal short-chain dehydrogenase domain with a cofactor binding site, and a narrow, hydrophobic C-terminal domain with a steroid substrate binding site. This gene is expressed primarily in the placenta and ovarian granulosa cells, and to a lesser extent, in the endometrium, adipose tissue, and prostate. Polymorphisms in this gene have been linked to breast and prostate cancer. A pseudogene of this gene has been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
抗原信息
免疫原
KLH conjugated synthetic peptide: human HSD17B1
抗原种属
Human
基因名称
HSD17B1
基因ID
蛋白名称
17-beta-hydroxysteroid dehydrogenase type 1
Uniprot ID
功能
Favors the reduction of estrogens and androgens. Also has 20-alpha-HSD activity. Uses preferentially NADH.
化学信息
分子量Theoretical: 35 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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