TROP-2 Protein, Human, Recombinant (Avi & His), Biotinylated

产品编号 TMPJ-00204

Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions. TROP-2 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 40-60 KDa and the accession number is P09758.

TROP-2 Protein, Human, Recombinant (Avi & His), Biotinylated

产品编号 TMPJ-00204

规格	价格	库存	数量
20 μg	¥ 2,260	5日内发货
100 μg	¥ 6,130	5日内发货

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生物活性

生物活性	1. Loaded Anti-Human TROP-2 mAb-Fc on Protein A Biosensor, can bind Biotinylated Human TROP-2-Avi-His with an affinity constant of 0.49 nM as determined in BLI assay. (Regularly tested) 2. Immobilized Biotinylated Human TROP-2-Avi-His at 1μg/ml (100 μl/well) can bind Anti-Human TROP-2 mAb. The ED50 of Anti-Human TROP-2 mAb is 4.19 ng/ml. (Regularly tested)
产品描述	Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions. TROP-2 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 40-60 KDa and the accession number is P09758.
种属	Human
表达系统	HEK293 Cells
标签	C-Avi-6xHis
蛋白编号	P09758
别名	TACSTD2,Cell surface glycoprotein Trop-2,Membrane component chromosome 1 surface marker 1,TROP2,Tumor-associated calcium signal transducer 2
氨基酸序列	His27-Thr274
蛋白构建	His27-Thr274
蛋白纯度	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量	40-60 KDa (reducing condition)
内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Tumor associated calcium signal transducer 2 (TACSTD2, TROP-2) is a type I cell surface glycoprotein that is highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors and is the second of two members of this family. Human and mouse TROP-2 share 87% amino acid (aa) similarity. TROP-2 is capable of transducing an intracellular calcium signal and may play a role in tumor growth. It also has adhesive functions.

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复溶计算器
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比活力计算器

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关键词

TACSTD 2 TROP 2 TACSTD-2 TROP-2