Name: Gepotidacin mesylate dihydrate
Brand: TargetMol
SKU: T70358
Price: 826 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 826

现货

5 mg

¥ 2,480

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10 mg

¥ 4,230

现货

25 mg

¥ 6,580

现货

50 mg

¥ 8,880

现货

100 mg

¥ 11,800

现货

200 mg

¥ 16,200

现货

1 mL x 10 mM (in DMSO)

¥ 3,160

现货

生物活性

产品描述	Gepotidacin mesylate dihydrate (GSK2140944 mesylate dihydrate) is an orally available triazaacenaphthylene antibiotic with antibacterial activity. Gepotidacin mesylate dihydrate is an inhibitor of bacterial type II topoisomerase. Gepotidacin mesylate dihydrate inhibits bacterial DNA replication by blocking topoisomerase and can be used to study bacterial infection.
靶点活性	positive superhelix substrate relaxation:0.6 μM, catalase-catalyzed DNA superhelix:0.047 μM, E. coli:1~4 mg/L (MIC)
体外活性	Gepotidacin mesylate dihydrate 是催化酶催化 DNA 超螺旋的有效抑制剂（IC50 ≈ 0.047 μM），并能抑制正超螺旋底物松弛（IC50 ≈ 0.6 μM）。[1] Gepotidacin mesylate dihydrate 对从穆勒-辛顿肉汤分离的大肠杆菌有抑制作用。MIC 为 1 至 4 mg/L。[2]
别名	吉珀达星甲磺酸水合物, GSK-2140944 mesylate dihydrate, GSK2140944 mesylate dihydrate, GSK 2140944 mesylate dihydrate

化学信息

分子量	580.65
分子式	C₂₅H₃₆N₆O₈S
CAS No.	1624306-20-2
Smiles	CS(=O)(O)=O.O=C1N(C2)C(N3[C@@H]2CN4CCC(CC4)NCC5=NC=C(OCCC6)C6=C5)=C(N=CC3=O)C=C1.O.O
颜色	Yellow
物理性状	Solid

储存&溶解度

存储	store at low temperature,keep away from moisture \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.