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Anti-CHRM1/M-AChR M1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CHRM1/M-AChR M1。Anti-CHRM1/M-AChR M1 Polyclonal Antibody 可用于 WB。
Anti-CHRM1/M-AChR M1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CHRM1/M-AChR M1。Anti-CHRM1/M-AChR M1 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-CHRM1/M-AChR M1 Polyclonal Antibody is a Rabbit antibody targeting CHRM1/M-AChR M1. Anti-CHRM1/M-AChR M1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Mouse (predicted:Human,Rat) |
| 验证活性 | 1. Sample: MCF-7 (Human) Cell Lysate at 30 μg Cerebellum (Mouse) Lysate at 40 μg Cerebrum (Mouse) Lysate at 40 μg Large intestine (Mouse) Lysate at 40 μg Primary: Anti-CHRM1’M-AChR M1 (TMAB-04317) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 51 kD Observed band size: 51 kD 2. Sample: MCF-7 (Human) Cell Lysate at 30 μg Cerebellum (Mouse) Lysate at 40 μg Cerebrum (Mouse) Lysate at 40 μg Large intestine (Mouse) Lysate at 40 μg Primary: Anti-CHRM1’M-AChR M1 (TMAB-04317) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 51 kD Observed band size: 51 kD 3. Sample: Cerebrum (Mouse) Lysate at 40 μg Cerebral cortex (Mouse) Lysate at 40 μg Primary: Anti-CHRM1’M-AChR M1 (TMAB-04317) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 51 kD Observed band size: 51 kD |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008]. |
| 免疫原 | KLH conjugated synthetic peptide: human CHRM1/M-AChR M1 |
| 抗原种属 | Human |
| 基因名称 | CHRM1 |
| 基因ID | |
| 蛋白名称 | Muscarinic acetylcholine receptor M1 |
| Uniprot ID | |
| 功能 | The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. |
| 分子量 | Theoretical: 51 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |