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别名 Small-inducible cytokine B11, SCYB9B, SCYB11, I-TAC, ITAC, H174, CXCL11, C-X-C motif chemokine 11, Beta-R1
CXCL11 Protein, Human, Recombinant (Active) is expressed in E. coli. The accession number is O14625.


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CXCL11 Protein, Human, Recombinant (Active) is expressed in E. coli. The accession number is O14625.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 569 | 6-8日内发货 | |
| 10 μg | ¥ 962 | 6-8日内发货 | |
| 20 μg | ¥ 1,630 | 5日内发货 | |
| 50 μg | ¥ 2,790 | 5日内发货 | |
| 100 μg | ¥ 4,760 | 5日内发货 |
| 产品描述 | CXCL11 Protein, Human, Recombinant (Active) is expressed in E. coli. The accession number is O14625. |
| 生物活性 | Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human IL-2 activated human T-lymphocytes is in a concentration range of 0.1-10 ng/ml. |
| 研究背景 | CXCL11 also known as I-TAC is belonging to the CXC chemokine family and shares 36 % and 37 % amino acid sequence homology with IP-10 and MIG, respectively. It is highly expressed in peripheral blood leukocytes, pancreas and liver. Expression of CXCL11 is strongly induced by IFN-γ and IFN-β, and weakly induced by IFN-α. This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3, which with a higher affinity than do the other chemokines for this receptor, CXCL9 and CXCL10. Similar to CXCL10, CXCL11 has been shown to be a chemoattractant for IL-2-activated T-lymphocytes, but not for isolated T-cells, neutrophils or monocytes. |
| 种属 | Human |
| 表达系统 | E. coli |
| 标签 | Tag Free |
| 蛋白编号 | O14625 |
| 氨基酸序列 | FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF |
| 蛋白构建 | Phe22-Phe94 |
| 蛋白纯度 | > 97% as determined by SDS-PAGE; > 97% as determined by HPLC |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from a 0.2 µm filtered concentrated solution in 20 mM PB, pH 7.4, 100 mM NaCl. |
| 复溶方法 | Reconstitute the lyophilized protein in sterile deionized water or aqueous buffer containing 0.1 % BSA. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | Small-inducible cytokine B11, SCYB9B, SCYB11, I-TAC, ITAC, H174, CXCL11, C-X-C motif chemokine 11, Beta-R1 |
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
| 分子量 | 8.3 kDa (Predicted) |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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