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别名 Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog, Myeloid/lymphoid or mixed-lineage leukemia protein 3, MLL3, Lysine N-methyltransferase 2C, KMT2C, Homologous to ALR protein, Histone-lysine N-methyltransferase MLL3
Anti-KMT2C Polyclonal Antibody 是一种 Rabbit 抗体,靶向 KMT2C。Anti-KMT2C Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。
Anti-KMT2C Polyclonal Antibody 是一种 Rabbit 抗体,靶向 KMT2C。Anti-KMT2C Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-KMT2C Polyclonal Antibody is a Rabbit antibody targeting KMT2C. Anti-KMT2C Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P. |
| 别名 | Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog, Myeloid/lymphoid or mixed-lineage leukemia protein 3, MLL3, Lysine N-methyltransferase 2C, KMT2C, Homologous to ALR protein, Histone-lysine N-methyltransferase MLL3 |
| Ig Type | IgG |
| 反应种属 | Mouse (predicted:Human,Rat,Pig) |
| 验证活性 | Paraformaldehyde-fixed, paraffin embedded (mouse testis tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (KMT2C) Polyclonal Antibody, Unconjugated (TMAB-01032) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining. ![]() |
| 应用 | IFIHC-FrIHC-P |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Highly expressed in testis and ovary, followed by brain and liver. Also expressed in placenta, peripherical blood, fetal thymus, heart, lung and kidney. Within brain, expression was highest in hippocampus, caudate nucleus, and substantia nigra. Not detect |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a nuclear protein with an AT hook DNA-binding domain, a DHHC-type zinc finger, six PHD-type zinc fingers, a SET domain, a post-SET domain and a RING-type zinc finger. This protein is a member of the ASC-2/NCOA6 complex (ASCOM), which possesses histone methylation activity and is involved in transcriptional coactivation. [provided by RefSeq, Jul 2008] |
| 免疫原 | KLH conjugated synthetic peptide: human KMT2C |
| 抗原种属 | Human |
| 基因名称 | KMT2C |
| 基因ID | |
| 蛋白名称 | Histone-lysine N-methyltransferase 2C |
| Uniprot ID | |
| 功能 | Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/MLL3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder. |
| 分子量 | Theoretical: 541 kDa. |
| 颜色 | White |
| 物理性状 | Oil |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | store at -20°C |