• TargetMol
    您的购物车当前为空

Anti-HOOK1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-07235

Anti-HOOK1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HOOK1。Anti-HOOK1 Polyclonal Antibody 可用于 WB。

Anti-HOOK1 Polyclonal Antibody

Anti-HOOK1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-07235

Anti-HOOK1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HOOK1。Anti-HOOK1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
库存状态实时更新,以官网显示为准,现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报,不能被用于人体,我们不向个人提供产品和服务。请您遵守承诺用途,不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:

产品介绍


生物活性
产品描述
Anti-HOOK1 Polyclonal Antibody is a Rabbit antibody targeting HOOK1. Anti-HOOK1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, cytoskeleton. Cytoplasm. Note=Localizes to the spermatid manchette during spermiogenesis but is not present in mature spermatozoa. Localizes to punctate cytoplasmic foci which do not appear to overlap with early or late endosomes, the endoplasmic reticulum, the Golgi complex, multivesicular bodies (MVBs), lysosomes, or mitochondria. Often found in close association with microtubules.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Microtubules mediate the spatial organization of diverse membrane-trafficking systems. The HOOK proteins, HOOK1, HOOK2 and HOOK3, comprise a family of cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules; and more divergent C-terminal domains, which mediate binding to organelles. HOOK1, a cytoskeletal linker protein, may play a role in endocytic membrane trafficking. It exists as a homodimer, most likely mediated through its central coiled-coil domain. HOOK1 interacts with VPS18 and is required for spermatid differentiation, in which it is most likely involved in the positioning of the manchette microtubules and the flagellum. HOOK1 localizes primarily to the cytoplasm and does not associate with the Golgi complex, unlike HOOK3, which participates in the organization of the cis-Golgi compartment.
抗原信息
免疫原
KLH conjugated synthetic peptide: Human HOOK1
抗原种属
Human
基因名称
HOOK1
基因ID
蛋白名称
Protein Hook homolog 1
Uniprot ID
功能
Required for spermatid differentiation. Probably involved in the positioning of the microtubules of the manchette and the flagellum in relation to the membrane skeleton. Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex).
化学信息
分子量Theoretical: 85 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
Related Tags: buy Anti-HOOK1 Polyclonal Antibody | purchase Anti-HOOK1 Polyclonal Antibody | Anti-HOOK1 Polyclonal Antibody cost | order Anti-HOOK1 Polyclonal Antibody | Anti-HOOK1 Polyclonal Antibody molecular weight