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Anti-METAP2 Antibody (7F524)

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Anti-METAP2 Antibody (7F524)
产品编号 TMAY-03339
别名 p67eIF2, p67, Mnpep, methionyl aminopeptidase 2, AU014659, Amp2, AL024412, AI047573, A930035J23Rik, 4930584B20Rik

Anti-METAP2 Antibody (7F524) 是一种 Rabbit 抗体,靶向 METAP2。Anti-METAP2 Antibody (7F524) 可用于 IHC-P。

Anti-METAP2 Antibody (7F524)
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Anti-METAP2 Antibody (7F524)

Rating icon 还可以
Anti-METAP2 Antibody (7F524)
产品编号 TMAY-03339 别名 p67eIF2, p67, Mnpep, methionyl aminopeptidase 2, AU014659, Amp2, AL024412, AI047573, A930035J23Rik, 4930584B20Rik

Anti-METAP2 Antibody (7F524) 是一种 Rabbit 抗体,靶向 METAP2。Anti-METAP2 Antibody (7F524) 可用于 IHC-P。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-METAP2 Antibody (7F524) is a Rabbit antibody targeting METAP2. Anti-METAP2 Antibody (7F524) can be used in IHC-P.
别名p67eIF2, p67, Mnpep, methionyl aminopeptidase 2, AU014659, Amp2, AL024412, AI047573, A930035J23Rik, 4930584B20Rik
Ig Type
Rabbit IgG
克隆号
7F524
交叉反应
Mouse
验证活性
1. Immunochemical staining of mouse METAP2 in mouse spleen with rabbit monoclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
2. Immunochemical staining of mouse METAP2 in mouse kidney with rabbit monoclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
3. Immunochemical staining of mouse METAP2 in mouse intestine with rabbit monoclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
应用
IHC-P
推荐剂量
IHC-P: 1:500-1:2000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse MAP2 (rM MAP2; TMPY-02727; O08663; Ala2-Tyr478).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景METAP2 (Methionine aminopeptidase 2), also known as MAP2 is a protein that belongs to the peptidase M24A family. MAP2 binds 2 cobalt or manganese ions and contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. It is found in all organisms and is especially important because of its critical role in tissue repair and protein degradation. The catalytic activity of human MAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. MAP2 protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. It also plays a critical role in the regulation of protein synthesis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Mouse MAP2 protein (TMPY-02727)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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