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Anti-METAP2 Antibody (7F524)
还可以产品编号 TMAY-03339
Anti-METAP2 Antibody (7F524) 是一种 Rabbit 抗体，靶向 METAP2。Anti-METAP2 Antibody (7F524) 可用于 IHC-P。
Anti-METAP2 Antibody (7F524)
Anti-METAP2 Antibody (7F524)
还可以产品编号 TMAY-03339
Anti-METAP2 Antibody (7F524) 是一种 Rabbit 抗体，靶向 METAP2。Anti-METAP2 Antibody (7F524) 可用于 IHC-P。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-METAP2 Antibody (7F524) is a Rabbit antibody targeting METAP2. Anti-METAP2 Antibody (7F524) can be used in IHC-P. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 7F524 |
| 交叉反应 | Mouse |
| 验证活性 | 1. Immunochemical staining of mouse METAP2 in mouse spleen with rabbit monoclonal antibody (1:1000, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of mouse METAP2 in mouse kidney with rabbit monoclonal antibody (1:1000, formalin-fixed paraffin embedded sections). 3. Immunochemical staining of mouse METAP2 in mouse intestine with rabbit monoclonal antibody (1:1000, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:500-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse MAP2 (rM MAP2; TMPY-02727; O08663; Ala2-Tyr478). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | METAP2 (Methionine aminopeptidase 2), also known as MAP2 is a protein that belongs to the peptidase M24A family. MAP2 binds 2 cobalt or manganese ions and contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. It is found in all organisms and is especially important because of its critical role in tissue repair and protein degradation. The catalytic activity of human MAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. MAP2 protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. It also plays a critical role in the regulation of protein synthesis. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse MAP2 protein (TMPY-02727) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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