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Anti-Phospho-SMAD2 (Ser250) Antibody (7J329)

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产品编号 TMAH-00963
别名 SMAD2 (p-Ser250), SMAD2 (p-S250), p-SMAD2 (Ser250), p-SMAD2 (S250), Phospho-SMAD2 (S250)

Anti-Phospho-SMAD2 (Ser250) Antibody (7J329) 是一种抗体,靶向 Phospho-SMAD2 (Ser250)。Anti-Phospho-SMAD2 (Ser250) Antibody (7J329) 可用于 ELISA, WB。

Anti-Phospho-SMAD2 (Ser250) Antibody (7J329)

Anti-Phospho-SMAD2 (Ser250) Antibody (7J329)

Rating icon 还可以
产品编号 TMAH-00963 别名 SMAD2 (p-Ser250), SMAD2 (p-S250), p-SMAD2 (Ser250), p-SMAD2 (S250), Phospho-SMAD2 (S250)

Anti-Phospho-SMAD2 (Ser250) Antibody (7J329) 是一种抗体,靶向 Phospho-SMAD2 (Ser250)。Anti-Phospho-SMAD2 (Ser250) Antibody (7J329) 可用于 ELISA, WB。

规格价格库存数量
50 μL
¥ 1,315
5日内发货
100 μL
¥ 2,195
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-SMAD2 (Ser250) Antibody (7J329) is an antibody targeting Phospho-SMAD2 (Ser250). Anti-Phospho-SMAD2 (Ser250) Antibody (7J329) can be used in ELISA, WB.
别名SMAD2 (p-Ser250), SMAD2 (p-S250), p-SMAD2 (Ser250), p-SMAD2 (S250), Phospho-SMAD2 (S250)
Ig Type
Rabbit IgG
克隆号
7J329
交叉反应
Human
验证活性
Western Blot
-Positive WB detected in Hela whole cell lysate,A549 whole cell lysate
-All lanes Phospho-SMAD2 antibody at 1.07μg/ml
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 58 KDa
-Observed band size: 58 KDa
应用
ELISA, WB
推荐剂量
WB:1:500-1:5000.
抗体种类
Monoclonal
亚细胞定位Cytoplasm. Nucleus.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human Phospho-SMAD2 (S250)
抗原种属
Human
基因ID
4087
Uniprot ID
研究领域
Signal Transduction
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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